Antitumor activity against human promyelocytic leukemia and studies of some benzoxazines.

Cancer is one of the deadliest diseases in the world today, and the incidence of cancer is increasing. Leukemia is a type of blood cancer defined as the uncontrolled proliferation of abnormal leukocytes in the blood and bone marrow. The HL-60 (human promyelocytic leukemia) cell line, derived from a single patient with acute promyelocytic leukemia, provides a unique model system for studying the cellular and molecular events involved in the proliferation and differentiation of leukemic cells.