Publications by authors named "Goya Seijirow"

Article Synopsis
  • Pimobendan is commonly used to treat heart failure in dogs, and a new injectable form has shown promise for intravenous use, but its effects via intramuscular (IM) injection have not been studied.
  • A study involving six healthy Beagle dogs compared the cardiovascular effects of IM and IV injections of pimobendan against a placebo, monitoring various clinical and echocardiographic parameters.
  • Results indicated that IM administration of pimobendan produced significant improvements in diastolic blood pressure and hemodynamic measurements over time, suggesting that IM use may be just as effective as the IV route.
View Article and Find Full Text PDF

Background: Novel non-invasive evaluation of the intraventricular pressure differences and gradients (IVPD and IVPG) by color M-mode echocardiography (CMME) is a promising method in diastolic function evaluation. Patent ductus arteriosus (PDA) is a congenital heart defect which is associated with increased preload. The present work provides a clinical trial for the assessment of IVPD and IVPG changes in dogs before and after surgical occlusion of PDA.

View Article and Find Full Text PDF

Although sildenafil is used in dogs with severe pulmonary hypertension, they sometimes become resistant and clinical signs deteriorate over time. The objective of this study was to determine the benefits of adjunct ambrisentan therapy in dogs with sildenafil-refractory pulmonary hypertension. In 5 dogs with severe pulmonary hypertension with deteriorating clinical signs despite ongoing sildenafil treatment, adding ambrisentan improved appetite, activity, and respiratory functions.

View Article and Find Full Text PDF

The type Aii shunt is a congenital extrahepatic portosystemic shunt (ePSS) involving the left and right gastric vein and the caudal vena cava (CVC). This report describes the case of a 6-month-old Italian greyhound diagnosed with a type Aii large-diameter ePSS. Staged surgeries were employed to completely ligate the 2 gastric veins and to avoid the risk of traumatizing the shunt vessel, CVC, and celiac artery.

View Article and Find Full Text PDF
Article Synopsis
  • PAWR is a phenomenon where blood flow from the right ventricle is reflected by the pulmonary arteries, creating a backward wave, and it can provide insights into pulmonary artery health, particularly in cases of pulmonary hypertension (PH).
  • Diagnostic cardiac catheterization methods are too invasive for routine use in small animals, so researchers explored a non-invasive technique using Doppler echocardiography to measure PAWR in dogs.
  • The study revealed that higher reflection coefficients (RC) are linked to suspected PH and shorter survival times, indicating its potential as a prognostic tool in veterinary medicine.
View Article and Find Full Text PDF

Early detection of doxorubicin (DXR)-induced cardiomyopathy (DXR-ICM) is crucial to improve cancer patient outcomes and survival. In recent years, the intraventricular pressure gradient (IVPG) has been a breakthrough as a sensitive index to assess cardiac function. This study aimed to evaluate the usefulness of IVPG for the early detection of chemotherapy-related cardiac dysfunction.

View Article and Find Full Text PDF

An 8-year-old, intact male miniature dachshund dog, weighing 8.6 kg, was presented with a soft swelling in the caudal abdominal region, including both sides of the groin area. Laparotomy revealed a severe caudal abdominal wall hernia with atrophy of the rectus abdominal muscle.

View Article and Find Full Text PDF

Pulmonic stenosis (PS) is the most common congenital heart disease in dogs and is commonly seen in small breeds, such as Chihuahuas. Conventional treatments have limitations specific to small dogs, including the invasive nature of open-heart surgery and size limitations in percutaneous balloon valvuloplasty. Here, transoesophageal echocardiography (TEE)-guided balloon valvuloplasty via thoracotomy was performed for three small dogs with PS.

View Article and Find Full Text PDF

The goal of this study was to evaluate diastolic intraventricular pressure gradients (IVPG) and 2-dimensional tissue tracking (2DTT) patterns during diabetes and cardiomyopathy. Rats ( = 60) were induced to become diabetic (DM group, = 15) by using streptozotocin, to become cardiomyopathic (CM group, = 15) by using isoproterenol, and to become both diabetic and cardiomyopathic (DMCM group, = 15); control rats (CT group, = 15) were injected with saline. Two months after induction, all rats underwent conventional echocardiography, IVPG, and 2DTT and then were euthanized for microscopic examination of cardiac fibrosis.

View Article and Find Full Text PDF

Pulmonary hypertension (PH) is a disease with poor prognosis, and it is characterized by the progressive elevation of pulmonary vascular resistance and pressure. Various factors are associated with the pathology of PH, including AMP-activated protein kinase (AMPK) deficiency. The present study aimed to evaluate the therapeutic effect of metformin, an AMPK activator, in a monocrotaline (MCT)-induced PH rat model.

View Article and Find Full Text PDF

Purpose: To study the diastolic functions using color Doppler M-mode (CDMM) for noninvasive analysis of the intraventricular pressure difference (IVPD) in diabetic rats.

Methods: Two equal groups of rats were included: control and streptozotocin-induced DM (n = 15). The cardiac functions were examined monthly using conventional echocardiography and CDMM with a specific MATLAB software.

View Article and Find Full Text PDF
Article Synopsis
  • Vorticity is a new measure that helps assess how well the left ventricle of the heart functions during the diastolic phase, which is when the heart fills with blood.
  • The size of the ventricle can greatly affect how blood flows during this filling phase, and the study evaluated this impact using a variety of dog breeds with different body sizes.
  • Results showed that vorticity decreases as the ventricular chamber length increases, indicating that size plays a crucial role in diastolic function, highlighting the importance of considering ventricular size in both veterinary medicine and pediatric cardiology.
View Article and Find Full Text PDF

The purpose of this study was to clarify how alacepril in amounts greater than those recommended on the product labeling approved by drug regulatory agencies affects left atrial pressure (LAP) and central aortic pressure in dogs with experimentally induced mitral valve regurgitation (MR). Six healthy Beagle dogs were surgically induced for MR and received alacepril at either 1.5mg/kg/12-h (3.

View Article and Find Full Text PDF

Restrictions on the conventional evaluation of diastolic function have been recognized, especially under various loading conditions. Recently, new noninvasive ventricular vortex indexes have been introduced and are expected to reflect the cardiac function. Physiologically, there is a hypothesis that the intraventricular pressure difference (IVPD) is related to the formation of vortexes.

View Article and Find Full Text PDF

A 7-year-old Miniature Schnauzer presented with exercise intolerance and easy fatigability. Echocardiography revealed the presence of supravalvular pulmonary stenosis. The peak velocity through the stenosis was 6.

View Article and Find Full Text PDF

Objective: To investigate the dose-dependent effects of isoflurane and dobutamine on haemodynamics in dogs with experimentally induced mitral valve insufficiency (MI).

Study Design: Experimental, dose-response study.

Animals: Six healthy Beagle dogs.

View Article and Find Full Text PDF

A 4-year-old, 5.9-kg female Japanese Spitz presented with syncope and exercise intolerance. Echocardiography revealed an ostium primum atrial septal defect (ASD), a cleft mitral valve, mitral valve regurgitation (MR), and tricuspid regurgitation (TR) (velocity: 3.

View Article and Find Full Text PDF

A 14-year-old intact male West Highland White Terrier weighing 6.9 kg was admitted to the Tokyo University of Agriculture and Technology Animal Medical Center with the complaint of syncope after showing signs of nausea during feeding. Sinus arrest induced by deglutition was confirmed using a Holter electrocardiography test.

View Article and Find Full Text PDF

Vector flow mapping (VFM) is a novel echocardiographic technology that shows blood flow vectors and vortexes, enabled the hydrokinetic evaluation of hemodynamics within the left ventricle. VFM provides several unique parameters: circulation, vorticity, vortex area, and energy loss. The present study aims to reveal a relationship between VFM parameters and cardiac function.

View Article and Find Full Text PDF

Background: After thoracic surgery, adhesions between the pleura can cause substantial complications. This study investigated the effectiveness of a novel membrane utilizing surface water induction technology to prevent adhesions.

Methods: Eight beagles were divided into an experimental group (five males) and a control group (three females).

View Article and Find Full Text PDF

Case Summary: A 13-month-old, female, mixed breed, 4.0 kg cat was referred with a 6 month history of decreased appetite, loss of vigour and intermittent vomiting. Physical examination revealed no cyanosis or wasting, and no audible heart murmur was auscultated.

View Article and Find Full Text PDF

The purpose of the present study is to investigate the effect of postural change on transesophageal echocardiography (TEE) views and parameters of interest anesthesia monitoring in healthy dogs. Twelve Beagle dogs were anesthetized and randomly positioned in one of four postures: right lateral-recumbency, left lateral-recumbency, supine position and prone position. After examinations in one posture, the same examination was demonstrated in another posture and repeated in all postures.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionfaot0s2l6rej5511jd4n24ntt5nkfd9m): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once