GC-MS/HPLC Profiling and Sono-Maceration Mediated Extraction of Osbeckia Parvifolia Polyphenols: In Silico and In Vitro Analysis on Anti-Proliferative Activity in Ovarian Cancer Cell Lines.

Osbeckia parvifolia, an endemic edible plant of Western Ghats, was investigated in the present study for its polyphenolic compounds, including content, constituents, extraction through an ultrasonic-assisted maceration technique and therapeutic potential in biomedical applications. The methanolic extract (OPM) exhibited an IC value of 1.25 μg/mL against 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radicals.

Elicitation of nutritional, antioxidant, and antidiabetic potential of barnyard millet (Echinochloa esculenta (A. Braun) H. Scholz) sprouts and microgreens through in vitro bio-accessibility assessment.

This study has redirected focus towards the untapped potential of millets, exploring their utilization as small-scale vegetables like sprouts and microgreens. This study assessed the metabolite profiles and therapeutic efficacy of barnyard millets as sprouts and microgreens for antioxidant, anti-diabetic, and bioaccessibility properties. Based on the study, sprouts contained 456.

Exploring the hypoglycaemic efficacy of bio-accessed antioxidative polyphenolics in thermally processed Cucumis dipsaceus fruits - An in vitro and in silico study.

Inhibition of breakdown of dietary carbohydrates, by controlling the postprandial activity of diabetic enzymes through fruit polyphenolics can help downregulate the effects of Type 2 Diabetes Mellitus (T2DM). The study focuses on deciphering the induction of hyperglycaemic control by bio-accessed anti-oxidative polyphenols of Cucumic dipsaceus fruits. Chiefly, we examined the antioxidant activity of bio-accessed polyphenols of C.

The effect of pulse pressure variation compared with central venous pressure on intraoperative fluid management during kidney transplant surgery: a randomized controlled trial.

Background: Traditionally, fluid administration during kidney transplant surgery is guided by central venous pressure (CVP) despite its limited reliability as a parameter for assessing intravascular fluid volume, particularly in patients with cardiovascular diseases. The recommended goals at graft reperfusion are a mean arterial pressure of 90 mm Hg and a CVP of 12-14 mm Hg. This approach may increase the risk of significant adverse effects due to volume overload.