Modulatory effect of Coccinia indica on aortic collagen in streptozotocin-induced diabetic rats.

1. The effects of Coccinia indica, an indigenous plant used in Ayurvedic medicine in India, on aortic collagen content and its characteristics were assessed in streptozotocin (STZ) diabetic rats. 2.

Similarity between the major collagens of cuttlefish cranial cartilage and cornea.

Invertebrates possess unique collagen-containing connective tissue elements, the biochemistry of which is not clearly understood. We previously reported the occurrence of a novel heterotrimeric type V/XI like collagen in the cranial cartilage of the cuttlefish Sepia officinalis. We report here the purification of the three chains by ion exchange chromatography and the physicochemical characteristics of this collagen.

Inhibition of collagen glycation and crosslinking in vitro by methanolic extracts of Finger millet (Eleusine coracana) and Kodo millet (Paspalum scrobiculatum).

The present investigation was carried out to study the effects of methanolic extracts of Finger millet (Eleusine coracana) and Kodo millet (Paspalum scrobiculatum) on glycation and crosslinking of collagen. Tail tendons obtained from rats weighing 200-225 g were incubated with glucose (50 mM) and 3 mg of extracts of the above millets in methanol under physiological conditions of temperature and pH for 10 days. Early glycation was estimated by phenol-sulfuric acid method and the crosslinking was assessed by pepsin digestion, cyanogen bromide peptide map and viscosity measurements.

Influence of Terminalia chebula on dermal wound healing in rats.

The effects of topical administration of an alcohol extract of the leaves of an evergreen plant, Terminalia chebula, on the healing of rat dermal wounds, in vivo, was assessed. T. chebula treated wounds healed much faster as indicated by improved rates of contraction and a decreased period of epithelialization.