Self-assembly of differently charged trimesic based lithocholic amphiphiles and their assessment on antimicrobial and biostimulant properties.

Biosurfactant based biostimulants plays a vital role in agriculture filed by enhancing the soil quality, promote plant growth, and eliminate plant pathogens, and increasing nutrient uptake. This manuscript describes the synthesis of trimesic based lithocholic ester functionalized amphiphiles (TMLCEA) with oppositely charged head groups using thiol-yne click chemistry, which is an effective and simple approach. The trimesic based lithocholic ester functionalized zwitterionic penicillamine (TMLCEPA), cationic cysteamine·HCl (TMLCECy), and anionic thiomalic acid (TMLCETM) exhibited hierarchically self-assembled microstructures from below to above the CMC.

Ultrathin Boron Growth onto Nanodiamond Surfaces via Electrophilic Boron Precursors.

Diamond as a templating substrate is largely unexplored, and the unique properties of diamond, including its large bandgap, thermal conductance, and lack of cytotoxicity, makes it versatile in emergent technologies in medicine and quantum sensing. Surface termination of an inert diamond substrate and its chemical reactivity are key in generating new bonds for nucleation and growth of an overlayer material. Oxidized high-pressure high temperature (HPHT) nanodiamonds (NDs) are largely terminated by alcohols that act as nucleophiles to initiate covalent bond formation when an electrophilic reactant is available.

Development and validation of the mobile adherence satisfaction scale (MASS) for medication adherence apps.

Objective: To develop and validate the Mobile Adherence Satisfaction Scale (MASS) for assessing user satisfaction with mobile health applications aimed to improve medication adherence.

Methods: The study involved patients over 18 with asthma, hypertension, heart failure, or diabetes, who used the CareAide® app for six months. Scale development included a literature review, expert consultations, and patient interviews, initially identifying 129 items.

Serum from patients with cirrhosis undergoing liver transplantation induces permeability in human pulmonary microvascular endothelial cells .

Introduction: Patients with cirrhosis undergoing liver transplantation frequently exhibit systemic inflammation, coagulation derangements, and edema, indicating endothelial dysfunction. This syndrome may worsen after ischemia-reperfusion injury of the liver graft, coincident with organ dysfunction that worsens patient outcomes. Little is known about changes in endothelial permeability during liver transplantation.

Highly flexible copper tape decorated with Ag nanoarrays as ultrasensitive SERS platforms for multi-hazardous pollutant sensing.

A highly flexible and cost-effective copper tape decorated with silver nanoparticles (Cu-TAg) has been developed for surface-enhanced Raman spectroscopy (SERS) sensing of multi-hazardous environmental pollutants. Highly ordered and spherical-shaped silver nanoarrays have been fabricated using a low-cost thermal evaporation method. The structural, morphological, and optical properties of Cu-TAg sensors have been studied and correlated to the corresponding SERS performances.

Using weather data to predict the presence of Lucilia spp. on sheep farms in New Zealand.

Flystrike remains an important animal health issue on New Zealand sheep farms. To date no useful predictive tool to assist farmers to develop control options has been available. The aim of this study was to use National Institute of Water and Atmospheric Research (NIWA) virtual climate station data in New Zealand to develop a weather-based model to accurately predict the presence of Lucilia spp.

Ethnic disparities and its association between epicardial adipose tissue thickness and cardiometabolic parameters.

Excessive deposit of epicardial adipose tissue (EAT) were recently shown to be positively correlated with cardiovascular disease (CVD). This study aims to investigate the thickness of EAT and its association with the components of metabolic syndrome among multi-ethnic Malaysians with and without acute coronary syndrome (ACS). A total of 213 patients were recruited, with the thickness of EAT were quantified non-invasively using standard two-dimensional echocardiography.

Exploring the rise of telehealth services in Malaysia: A retrospective study.

Background: Telehealth services have gained popularity in Malaysia, providing convenient consultations during the COVID-19 pandemic. However, there is limited research on their usage, user demographics and prescribed medications. This study aims to fill that gap by investigating telehealth service utilisation in community pharmacies and identifying trends in common diagnoses and medications prescribed.

Mesenchymal stem cell-derived extracellular vesicles for metabolic syndrome therapy: Assessing efficacy with nuclear magnetic resonance spectroscopy.

Metabolic syndrome (MetS) represents a cluster of metabolic abnormalities. The prevalence of MetS has surged, transforming it into a pressing public health concern that could potentially affect around 20%-25% of the global population. As MetS continues its ascent, diverse interventions, pharmacological, nonpharmacological and combined have been deployed.

Practice and knowledge of dietary supplement consumption among Indonesian adults post-delta wave of the COVID-19 pandemic.

Increasing dietary supplement (DS) consumption was observed during the COVID-19 pandemic, including during the post-Delta wave period. This study aimed to measure the practice of DS consumption and respondents' knowledge of DS. An internet-based survey was distributed from October-December 2021 and obtained 541 valid and completed responses.

Carbon offset potential of biochar based straw management under rice- wheat system along Indo-Gangetic Plains of India.

The Paris Agreement goal of a net-zero equation will require decarbonization technologies in agriculture. Agri-waste biochar offers huge potential for carbon abatement in agricultural soils. The present experiment was carried out to compare the effects of residue management, viz.

Biodeterioration of polyethylene by jellyfish nematocyst protein.

Plastic pollution is one of the major global problems existing now-a-days and has become a cause of serious concern in coastal and marine ecosystems. Increased accumulation of plastics in the aquatic environment by anthropogenic sources results the alteration of the aquatic ecosystem and its functioning. Several variables have an impact on biodegradation, ranging from microbe species to polymer type, physicochemical qualities, and environmental circumstances.

Isolation, characterization, and utilization of wheat bran protein fraction for food application.

Wheat bran (WB), a low-cost industrial by-product, is a vital source of high-quality proteins, minerals, vitamins, and several bioactive compounds. The present study encompasses the identification of appropriate bran streams of a commercial roller flour mill (CRFM) essentially based on hector liter weight, (HLW), optimization of WB protein isolation process, amino acid characterization, rendering more emphasis on simple water-soluble albumins, having higher commercial viability, and its application in food formulation. Total WB protein was 16.

Downer cows: a reanalysis of an old data set.

Aims: To compare the performance of two predictive models for the survival of downer cows.

Methods: The first model had been developed in 1987 using a dataset containing missing values, while the second, new model was developed on the same dataset but using modern data imputation and analytical methods. Missing data were imputed using multiple imputation by chained equations and a logistic regression model fitted to the imputed data, with survival or not as the outcome variable.

Optimizing Antimicrobial Therapy by Integrating Multi-Omics With Pharmacokinetic/Pharmacodynamic Models and Precision Dosing.

In the era of "," optimizing antibiotic therapy against multi-drug resistant (MDR) pathogens is crucial. Mathematical modelling has been employed to further optimize dosing regimens. These models include mechanism-based PK/PD models, systems-based models, quantitative systems pharmacology (QSP) and population PK models.

Silver nanoparticles based spectroscopic sensing of eight metal ions in aqueous solutions.

Anthropogenic releases from different outlets of industry, municipal sewage and the road traffic can give rise to higher concentrations of heavy metals in food commodities which imposes a threat to human health and environment. A simple silver nanoparticle (Ag NPs) used for the sensing of heavy metal ions, Cd, Cu, Fe, Hg, Mn, Ni, Pb and Zn in aqueous solution is described qualitatively and quantitatively using spectroscopic tool. FE-SEM and TEM images confirmed that the particles are spherical in shape with an average diameter of 23.

Biogenic preparation of ZnO, CaO, and ZnO-CaO nanocomposites and its influence on agro-morphological characteristics of mung bean.

In this study, nanomaterials (ZnO and CaO) and ZnO-CaO nanocomposites (ZnCaO; ZnCaO; ZnCaO) were prepared using co-precipitation method and physico-chemically characterized by XRD, FT-IR, and SEM with EDAX analysis. The XRD pattern of ZnO nanomaterials exhibits hexagonal wurtzite structure and CaO nanomaterials exhibit face-centered cubic (FCC) structure whereas nanocomposites (ZnCaO, ZnCaO, ZnCaO) exhibit both hexagonal phase of ZnO and cubic phase of CaO. The SEM images of ZnO-CaO nanocomposites show the well-distributed clusters composed of ZnO and CaO nanoparticles with most of the particles are spherical and some of the particles are rod- and cubic-like morphology.

Biosynthesis of reduced graphene oxide using Turbinaria ornata and its cytotoxic effect on MCF-7 cells.

Graphene-based nanomaterials are gaining importance in biomedicine because of their large surface areas, solubility, and biocompatibility. Green synthesis is the most economical method for application, as it is rapid and sustainable. Biofunctionalized reduced graphene oxide (TrGO) nanosheets were synthesized using methanol extract of Turbinaria ornata, and bioreduction of graphene oxide was primarily confirmed and characterized using UV-visible, Fourier transform infrared (FTIR), and X-ray diffraction spectroscopy and further characterized by zeta potential and transmission electron microscopy.

Evidence-based traditional Siddha formulations for prophylaxis and management of respiratory symptoms in COVID-19 pandemic-a review.

The recent outbreak of COVID-19 is attributed to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This viral disease is rapidly spreading across the globe, including India. The mainstay in managing the disease is supportive care, nutrition, and preventing further progression in the absence of proven antiviral drugs.

Ameliorative effect of enhanced Fischer ratio flaxseed protein hydrolysate in combination with antioxidant micronutrients on ethanol-induced hepatic damage in a rat model.

Alcohol abuse causes severe metabolic abnormalities inducing hepatic damage and malnutrition. Since higher Fischer ratio proteins have therapeutic value in liver diseases, an investigation was undertaken to study the ameliorative effect of the enhanced Fischer ratio flaxseed protein hydrolysate (EFR-FPH) alone and in combination with antioxidant micronutrients on ethanol-induced hepatotoxicity in a rat model. The EFR-FPH was prepared by dual enzymatic hydrolysis and charcoal treatment of flaxseed protein.

Influence of nanoscale micro-nutrient α-FeO on seed germination, seedling growth, translocation, physiological effects and yield of rice (Oryza sativa) and maize (Zea mays).

In the present study, nanoscale micronutrient iron (α-FeO) has been prepared via co-precipitation using marine macro alga Turbinaria ornata. The nanoscale micronutrient iron has been used as priming agent for enhancing seed germination, seed quality, uptake, translocation, physiological effects and yield level of rice and maize crops. The physico-chemical characterization techniques results showed the successful preparation of nanoscale micronutrient iron.

Jellyfish venom proteins and their pharmacological potentials: A review.

Several research in the organisms of marine invertebrates to assess the medicinal ability of its bio-active molecules have yielded very positive results in recent times. Jellyfish secreted venoms are rich sources of toxins intended to catch prey or deter predators among invertebrate species, but they may also have harmful effects on humans. The nematocyst, a complex intracellular system that injects a venomous mixture into prey or predators that come into contact with the tentacles or other parts of the body of cnidarians, determines the venomous existence of cnidarians.

anti-diabetic assessment of guavanoic acid functionalized gold nanoparticles in regulating glucose transport using L6 rat skeletal muscle cells.

Guavanoic acid functionalized gold nanoparticles exhibit anti-diabetic potential by improving insulin dependent glucose uptake in L6 rat skeletal muscle cells. The mode of action of the gold nanoparticles was established from the glucose uptake assay in the presence and absence of genistein and wortmannin. The anti-diabetic efficacy of guavanoic acid functionalized gold nanoparticles was put forth by assays like for PTP 1B, α-amylase and α-glucosidase enzyme activities.

Ultra-structural and physico-chemical characterization of eggs and egg hairs (setae) of the new invasive pest, fall armyworm, Spodoptera frugiperda (J. E. Smith) in India: A first report.

In this study, we report first time in India on the morphology, ultra-architectural pattern of the chorion in the egg and egg hair (setae). Further, physico-chemical characterizations of egg hairs (setae) were studied in the new invasive pest, fall armyworm, Spodoptera frugiperda. The egg is dome shaped with flattened base and curves upward to a broadly rounded point at the apex.

Synthesis, characterization and anti-inflammatory properties of karanjin (Pongamia pinnata seed) and its derivatives.

Karanja (Pongamia pinnata) is a medicinal tree used in the Indian traditional ayurvedic system for treating several ailments. The seeds contain a unique furano-flavonoid karanjin, which has shown to possess many medicinal properties. Its usage at the clinical level is affected due to poor solubility and absorption.