Publications by authors named "Govindaraj Varadaraj"

Article Synopsis
  • A 48-year-old man with a history of mitral valve replacement and recent ischemic stroke experienced sudden angina and had not taken his anticoagulant medication for 50 days.
  • Upon examination, he exhibited severe hemodynamic instability, which was resolved using intravenous diltiazem, leading to stabilized blood pressure and heart rate.
  • Due to the unavailability of surgical options, he received thrombolytic treatment with Alteplase for prosthetic mitral valve thrombosis, resulting in improved valve function and symptom relief within 6 hours; he is now on strict anticoagulant therapy.
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Background: Acute undifferentiated fever (AUF) is defined as any febrile illness with a duration of ≤14 days without evidence of localized infection. Most outpatient services and a significant inpatient load in India are contributed by AUF. COVID-19 has recently added to the existing list of common etiologies of AUF.

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Background: There were widespread unconfirmed reports about the increased severity of dengue post-second wave of the COVID-19 pandemic in India. It is known that a second dengue infection with a different strain in an individual can trigger antibody-dependent enhancement (ADE). A similar phenomenon is hypothesized for severe COVID-19 infection since both dengue and COVID-19 are viral diseases with different and varying strains.

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