The place of psychoanalysis in French psychiatry.

France is known as one of the countries where psychoanalysis still holds an important position in various fields, and specially in psychiatry. Is it a 'culture bound syndrome' of French society, or, more seriously, a particularity that could be useful in other contexts as well? Through consideration of the role psychoanalysis is playing in French psychiatry, this paper will try to review this particularity and its interactions with the organisation and values of psychiatry in France, both in the public services and in private practice.

[From the perinatal period to adolescence: the three stages of coordination].

The need for coordinated organisation between infant-child psychiatry and adult psychiatry is highlighted through key periods, with the aid of a clinical case: the perinatal period and the hospitalisation of a mother with her child; the psychiatric support of the unwell mother and that of her daughter; then the transition for the 16-year-old teenager towards adult psychiatry. Taking into consideration the mother-child bond is essential and requires collaborative care projects, the creation of opportunities for joint reflection and organisation, and the acknowledgement that internal institutional divisions exist which are too often denied.

Occupational identity crisis of professionals dealing with difficult adolescents.

This study tests the hypothesis of vulnerability in health and social care professionals dealing with difficult adolescents. This vulnerability appears to be underpinned by an occupational identity crisis that seems to diminish the ability of these professionals to recognize the suffering of these adolescents. A questionnaire was developed and then distributed during a network day bringing together members of various institutions and bodies working with difficult adolescents.

Experimental evidence of the electrostatic contribution to the bending rigidity of charged membranes.

We address the issue of the origin of the bending rigidity of a charged membrane formed from amphiphilic molecules. Electrostatic effects are investigated by direct measurement of the force necessary to deform a catanionic membrane as function of the ionic strength of the medium by means of an atomic force microscope (AFM). Using continuum mechanical modeling of membrane deformation, we derive the bending rigidity of the catanionic membranes and monitor for the first time its decrease in response to increasing salt concentration.

Anti-lactoferrin autoantibodies: relation between epitopes and iron-binding domain.

Anti-neutrophil cytoplasm antibodies (ANCA) have been found in the sera of patients presenting systemic necrotizing microscopic vasculitis, i.e. Wegener's granulomatosis and microscopic polyangiitis.

Flow cytometry analysis of dual red blood cell populations after bone marrow transplantation.

Flow cytometry represents an alternative method to agglutination assays for the accurate quantification of mixed field populations of erythrocytes observed after bone marrow transplantation. Murine monoclonal antibodies directed against the blood group ABH antigens were selected and processed in order to prepare ready-to-use fluorescent reagents. Anti-A (NaM87-1F6; IgG3), anti-B (NaM9-2E11; IgG3) and anti-H (NaM19-7E11; IgM) were purified, labelled with fluorescein isothiocyanate, and used in a direct flow cytometry assay.

Variation in fetal hemoglobin parameters and predicted hemoglobin S polymerization in sickle cell children in the first two years of life: Parisian Prospective Study on Sickle Cell Disease.

Intracellular hemoglobin S (HbS) polymerization is most likely to be the primary determinant of the clinical and biologic manifestations of sickle cell disease (SCD). Fetal hemoglobin (HbF) does not enter the HbS polymer and its intracellular expression in sickle erythrocytes inhibits polymerization. HbF levels, high at birth but decreasing thereafter, protect the newborn from the clinical manifestations of this hemoglobinopathy.

A murine monoclonal antibody directed against the Gerbich 3 blood group antigen.

A murine monoclonal antibody (NaM19-3C4, IgG1, Kappa) was produced from splenocytes of mice immunized with red blood cells. The antibody agglutinated untreated Ge:2,3,4 and Ge:-2,3,4 erythrocytes in indirect antiglobulin test but failed to agglutinate trypsin-treated cells. Gerbich-negative erythrocyte of the Leach- (Ge:-2,-3,-4) and of the Gerbich- (Ge:-2,-3,4) types were not recognized by the antibody.