Evaluation of Salivary Transcriptome Markers for the Early Detection of Oral Squamous Cell Cancer in a Prospective Blinded Trial.

Background: Oral squamous cell cancer (OSCC) is often diagnosed in late stages. Informative biomarkers could play a key role in early diagnosis. Prior case-control studies identified discriminatory salivary mRNA markers for OSCC.

Reagent strip diagnosis of UTI in a high-risk population.

A study was undertaken to determine the accuracy of reagent strip diagnosis of urinary tract infection (UTI) in patients seen in the ED who were subsequently admitted to hospital with this diagnosis. The reagent strip results of 100 patients were recorded and the sensitivity and specificity of various parameters in the diagnosis of UTI were calculated. Our results indicate that even in a group of patients with high clinical probability of UTI and with symptoms severe enough to be hospitalized, reliance on positivity of any single parameter alone gives unacceptably low sensitivity: 89%, 39%, 68%, and 63% for WBC, nitrite, RBC, and protein, respectively.

Adult patients with occult bacteremia discharged from the emergency department: epidemiological and clinical characteristics.

To determine the epidemiological and clinical characteristics of patients who were discharged from the emergency department (ED) and subsequently proved to have bacteremia, we prospectively assessed all patients examined in the ED during an 18-month period from whose blood cultures a significant organism was isolated. Discharged patients were contacted and reevaluated. Two case-control studies were conducted, in which each study patient was matched with a total of 4 control patients.

Air abrasion: fixing the cutting edge.

The cutting edges of the anterior teeth can be preserved and/or restored using proper concepts and instrumentation. Air abrasion is uniquely well-suited for preparing the class VI restoration.

Cost-effectiveness of blood cultures for adult patients with cellulitis.

To assess the cost-effectiveness of blood cultures for patients with cellulitis, a retrospective review was conducted of clinical and microbiological data for all 757 patients admitted to a medical center because of community-acquired cellulitis during a 41-month period. Blood cultures were performed for 553 patients (73%); there were a total of 710 blood samples (i.e.

Ten-year follow-up study of hepatitis B virus infection and vaccination status in hospital employees.

We sought to determine the incidence of infection with hepatitis B virus (HBV) amongst hospital employees over a 10-year period and to assess the extent and efficacy of vaccination against HBV in this population. In 1984 a cohort of 301 hospital employees was tested for hepatitis B surface antibody (anti HBs), hepatitis B core antibody (anti HBc), and hepatitis B surface antigen (HBsAg). Ten years later, 160 (53%) of these workers remained at the hospital and were re-tested.

Power scalers: the new boom in contemporary periodontics.

The choice of which type of instrumentation to use remains the decision of the practitioner. It all depends on what goal the clinician hopes to achieve, the resources, and the physical set up within which they work. While speed in debridement, coupled with ease of use and comfort to the patient and practitioner are all important, the primary goal must always remain the optimal healing and success of the dental procedure.