Association of body mass index with pathologic agreement of preoperative and postoperative tumor grade in endometrial cancer.

Objective: We aim to study association of BMI of EC patients, with the level of agreement between preoperative and postoperative tumor grade.

Methods: A retrospective study. We included patients with EC diagnosed in an outpatient clinic which had surgical staging as in our division.

Global distribution and career outcomes of international fellows trained in Canadian gynecologic oncology programs.

Objective: We assessed the global distribution and academic, administrative and research outcomes of international fellows (IFs) trained in Canadian gynecologic oncology (GO) programs.

Methods: A web-based survey was sent to IFs who completed GO training in Canada. Using the Web of science database, we identified the publication list, citation record and H-index of IFs and classified them according to their region of practice: high-income countries (HIC), middle income countries (MIC), and low-income countries (LIC).

GD2 and GD3 gangliosides as prognostic biomarkers in high grade serous ovarian cancer.

Objective: Gangliosides GD2 and GD3 have been proposed to be of significance in diagnosis of ovarian masses. We aim to study serum GD2 and GD3 gangliosides as predictors of oncological outcomes among high grade serous (HGS) ovarian cancer (OC).

Materials And Methods: A retrospective study including biobanked serum samples of HGS OC treated between 2005 and 2016.

Ascites and Serum Interleukin-10 Levels as a Prognostic Tool for Ovarian Cancer Outcomes.

Interleukin-10 (IL-10) has been shown to be present at high levels in the ascites of ovarian cancer (OC) patients; however, little is known about its prognostic value. We sought to correlate IL-10 levels in ascites and sera of OC patients with clinicopathologic characteristics and oncologic outcomes. IL-10 levels and clinical data from biobanked ascites and serum samples of OC patients were evaluated.

Robotic Surgery in Gynecologic Oncology-A Bibliometric Study.

Study Objective: To characterize robotic surgery publications in gynecologic oncology, and to identify factors associated with high citation metrics.

Design: A cross-sectional study SETTING: Original articles on robotic surgery in gynecologic oncology.

Patients: No patients involved.

Surgery Advances in Gynecologic Tumors: The Evolution and Outcomes of Robotic Surgery for Gynecologic Cancers in a Tertiary Center.

The integration of innovation into routine clinical practice is faced with many challenges. In 2007, we received the mandate to evaluate how the introduction of a robotic program in gynecologic oncology affected patient-centered care by studying its impact on clinical outcomes and hospital resource utilization. Here we summarize the history and experience of developing a robotic surgery program for gynecologic cancers over 16 years.

Gynecologic oncology robot-assisted surgery in octogenarians: Impact of age on hospital stay.

Objective: To compare postoperative stay in octogenarians and younger patients undergoing gynecologic oncology robot-assisted surgery.

Methods: A retrospective review of robot-assisted surgery in Gynecological Oncology division during 2019-2022. We included all consecutive cases.

Interleukine-10 in ovarian cancer.

Interleukins serve as communicating molecules between cells, mediating key interactions in the tumor microenvironment (TME) between immune cells and non-immune cells. Interleukin-10 (IL-10), a multifunctional cytokine with multiple properties, has been extensively studied in various aspects of immunology and cancer biology. IL-10 is pleiotropic, promotes cytotoxicity, yet inhibits antitumor-responses.

Association between BMI and oncologic outcomes in epithelial ovarian cancer: a predictors-matched case-control study.

Objective: We aimed to study the association between obesity and survival in ovarian cancer (OC) patients, accounting for confounders as disease stage, histology, and comorbidities.

Methods: Retrospective matched case-control study of consecutive patients, with epithelial OC. Obese (body mass index [BMI] ≥ 35 kg m) patients were matched in a 1:4 ratio with patients having lower BMIs (BMI < 35 kg m) based on disease stage, cytoreduction state, tumor histology and ASA score.

Gynecologic perivascular epithelioid cell tumors (PEComas): a review of recent evidence.

Gynecologic perivascular epithelioid cell (PEC) tumors, or 'PEComas,' represent a rare and intriguing subset of tumors within the female reproductive tract. This systematic literature review aims to provide an updated understanding of gynecologic PEComas based on available literature and data. Although PEComa is rare, there are varied tumor-site presentations across gynecologic organs, with uterine PEComas being the most prevalent.

The value of multicenter collaboration in Gynecologic Oncology research.

Introduction: Canadian gynecological oncology (GYNONC) is constantly evolving. We aim to study the patterns in Canadian GYNONC research using a systematic search approach and bibliometric analysis.

Evidence Acquisition: We used Web of Science to identify all relevant publications in the field of GYNONC by Canadian.

The impact of body mass index on robotic surgery outcomes in endometrial cancer.

Objectives: To compare surgical outcomes of patients with endometrial cancer who underwent robotic surgery across different BMI categories.

Methods: A retrospective study including all consecutive patients with endometrial cancer who underwent robotic surgery at a tertiary cancer center between December 2007 and December 2022. The study analyzed outcome measures, including blood loss, surgical times, length of hospitalization, perioperative complications, and conversion rates with the Kruskal-Wallis test for BMI group differences and the Chi-squared test for associations between categorical variables.

Machine learning for prediction of concurrent endometrial carcinoma in patients diagnosed with endometrial intraepithelial neoplasia.

Objective: To identify predictive clinico-pathologic factors for concurrent endometrial carcinoma (EC) among patients with endometrial intraepithelial neoplasia (EIN) using machine learning.

Methods: a retrospective analysis of 160 patients with a biopsy proven EIN. We analyzed the performance of multiple machine learning models (n = 48) with different parameters to predict the diagnosis of postoperative EC.

The Impact of Intrauterine Manipulators on Outcome and Recurrence Patterns of Endometrial Cancer Patients Undergoing Minimally Invasive Surgery.

To evaluate the use of manipulators on the outcome of women who had minimally invasive surgery for endometrial cancer. Retrospective analysis of patients operated with or without an intrauterine manipulator. Six hundred ninety-nine patients were included.

Robotic surgery in obstetrics and gynecology: a bibliometric study.

We aimed to identify the trends and patterns of robotic surgery research in obstetrics and gynecology since its implementation. We used data from Clarivate's Web of Science platform to identify all articles published on robotic surgery in obstetrics and gynecology. A total of 838 publications were included in the analysis.

GD2 and GD3 gangliosides as diagnostic biomarkers for all stages and subtypes of epithelial ovarian cancer.

Background: Ovarian cancer (OC) is the deadliest gynecological cancer, often diagnosed at advanced stages. A fast and accurate diagnostic method for early-stage OC is needed. The tumor marker gangliosides, GD2 and GD3, exhibit properties that make them ideal potential diagnostic biomarkers, but they have never before been quantified in OC.

Gynecological Cancer Survivors' Experiences of Dyspareunia and Factors Influencing Care-Seeking Behavior: A Qualitative Study.

Pain during sexual intercourse, also called dyspareunia, affects most women after treatment for gynecological cancer. Previous work adopted a biomedical approach to depict dyspareunia in this population, which provided a narrow perspective of this condition. Taking into account women's experiences of dyspareunia and the factors influencing their care-seeking behaviors would provide insight to improve care in the context of gynecological cancer.

Alcohol intake and the risk of epithelial ovarian cancer.

Purpose: To investigate the association between alcohol intake over the lifetime and the risk of overall, borderline, and invasive ovarian cancer.

Methods: In a population-based case-control study of 495 cases and 902 controls, conducted in Montreal, Canada, average alcohol intake over the lifetime and during specific age periods were computed from a detailed assessment of the intake of beer, red wine, white wine and spirits. Multivariable logistic regression was used to estimate odds ratios (ORs) with 95% confidence intervals (CIs) for the association between alcohol intake and ovarian cancer risk.