Tick Tock-A Matter of Time: Two Cases of Babesia Acquired in Urban Newark, NJ.

Babesiosis is a parasitic tick-borne infectious disease that is well elucidated in medical literature and known to be endemic to the Midwest and northeast United States. However, like other infectious diseases, its epidemiology is subject to change. This case report documents two cases with clinical presentations that deviate from what is expected in typical cases of Babesiosis.

Endocarditis Presenting with Brain Abscesses and Temporal Vision Deficits.

is a coagulase-negative staphylococcal bacterium (CoNS) that colonizes the skin. While infectious endocarditis (IE) caused by is rare, it is noteworthy because it has been associated with an aggressive clinical course. In this report, we present a case of culture-negative IE complicated by brain abscesses, vision deficits, and progressive heart failure that ultimately required mitral valve replacement.

Impact of Rapid Identification and Stewardship Intervention on Coagulase-Negative Bloodstream Infection.

We investigated the impact of rapid diagnostic testing with and without algorithm-based stewardship recommendations on antibiotic use for bloodstream infection with coagulase-negative staphylococci. A significant reduction in antibiotic days of therapy was achieved in the stewardship intervention group that was not seen with rapid diagnostic testing alone.

Effects of complex tonal stimuli on latency and amplitude of a late auditory evoked potential.

An optimum stimulus for evoking late auditory potentials is not well established. A typical stimulus for clinical purposes is either a brief speech signal or a brief single-frequency tone. Based on previous research, it is reasonable to assume that a complex stimulus may enhance waveform morphology relative to a single-frequency stimulus.

Decreasing sound and vibration during ground transport of infants with very low birth weight.

Objective: To measure the effectiveness of modifications to reduce sound and vibration during interhospital ground transport of a simulated infant with very low birth weight (VLBW) and a gestational age of 30 weeks, a period of high susceptibility to germinal matrix and intraventricular hemorrhage.

Study Design: Researchers measured vibration and sound levels during infant transport, and compared levels after modifications to the transport incubator mattresses, addition of vibration isolators under incubator wheels, addition of mass to the incubator mattress and addition of incubator acoustic cover.

Result: Modifications did not decrease sound levels inside the transport incubator during transport.

Temporal-order judgment of audiovisual events involves network activity between parietal and prefrontal cortices.

Our perception of the temporal order of everyday external events depends on the integrated sensory information in the brain. Our understanding of the brain mechanism for temporal-order judgment (TOJ) of unisensory events, particularly in the visual domain, is advanced. In case of multisensory events, however, there are unanswered questions.

P1 amplitude across replicates: does measurement method make a difference?

Purpose: Most cortical auditory evoked potentials instruments provide a "default" peak-to-baseline (P-B) amplitude and a means for obtaining a peak-to-trough (P-T) measure. This study investigated the sensitivity of these two measures in assessing the effects of repeated runs on the P1 component of the electrophysiological response.

Methods: Cortical auditory evoked potentials were recorded on 30 normal hearing young adults.

Neurite elongation on chondroitin sulfate proteoglycans is characterized by axonal fasciculation.

In the developing or regenerating nervous system, migrating growth cones are exposed to regulatory molecules that positively and/or negatively affect guidance. Chondroitin sulfate proteoglycans (CSPGs) are complex macromolecules that are typically negative regulators of growth cone migration in vivo and in vitro. However, in certain cases, neurites sometimes traverse regions expressing relatively high levels of CSPGs, seemingly a paradox.

Subretinal neovascularization in children and adolescents.

Subretinal neovascular membranes (SRNVM) in the pediatric population are rare. The clinical presentation, etiology, course, and management of SRNVM in 25 children (27 eyes) were studied retrospectively. Inflammatory or infectious conditions predominated (10 of 25).

Effects of intensity on speech recognition in high- and low-frequency bands.

Objective: This study investigated the intensive effects of a low-frequency (200 to 400 Hz) and a high-frequency (1000 to 5000 Hz) band of speech presented jointly and in isolation.

Design: Each band was presented at a reference intensity level equivalent to the average normal conversational level. To investigate intensive effects, the low-frequency band was presented at 20 dB and 36 dB, and the high-frequency band at 20 dB above the reference level.

Auditory reaction times for functional and nonfunctional hearing loss.

Differences in decision processes as measured by auditory reaction times of simulated or actual functional hearing-loss subjects and nonfunctional subjects were investigated. Sensation level data are presented that reflect marked differences between such individuals with regard to probability of response, and means and standard deviations of auditory reaction times. Means and standard deviations of auditory reaction times for nonfunctional subjects are greatly reduced when compared with results obtained by simulated or actual functional subjects.