Publications by authors named "Goshima S"

Background And Objective: The association between interstitial lung abnormalities (ILA) and various conditions and diseases, including drug-related pneumonitis (DRP), has been reported. However, the association of the presence of ILA with developing DRP in patients undergoing cytotoxic agent-based chemotherapy, one of the standard treatments for malignancies, remains unclear. This warrants urgent investigation.

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  • Immune-related pneumonitis (irP) is a significant side effect of immune checkpoint inhibitors, often relapsing after corticosteroid treatment, which complicates cancer therapy.* -
  • A study analyzed 56 patients with irP and found that 39.3% experienced relapses post-prednisolone therapy; significant risk factors included a radiographic pattern of organizing pneumonia and an onset of irP more than 100 days after starting treatment.* -
  • Identifying these risk factors is crucial for better managing irP in patients undergoing treatment, as it could lead to improved outcomes.*
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  • The study aimed to evaluate the effectiveness of deep learning reconstruction (DLR) on the quality of computed tomography hepatic arteriography (CTHA) images taken during transcatheter arterial chemoembolization (TACE).
  • Twenty-seven patients were analyzed using three different reconstruction algorithms: hybrid-iterative reconstruction (hybrid-IR), DLR with mild strength (DLR-M), and DLR with strong strength (DLR-S).
  • Results showed that DLR-S provided significantly better image quality, with higher signal-to-noise ratios and superior sharpness for vascular structures and tumors compared to the other algorithms, although feeder artery detection rates were similar across all methods.
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A 56-year-old man was born to consanguineous parents. He experienced slow-progressing sensory disturbances in the upper extremities. T1-weighted images showed cerebellar atrophy.

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Obtaining an imaging diagnosis of various hepatobiliary and pancreatic disorders caused by certain drugs can often be challenging. Familiarity with these conditions may improve diagnostic accuracy and patient management. This review aimed to describe the imaging findings of drug-associated hepatobiliary and pancreatic disorders and identify suggestions for obtaining a correct diagnosis.

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Background And Objective: The lung immune prognostic index (LIPI), a simple index calculated from the blood lactate dehydrogenase level and derived neutrophil-to-lymphocyte ratio, is thought to be associated with host immune status. However, the utility of LIPI in patients with idiopathic interstitial pneumonias (IIPs) is unknown.

Methods: In this multicentre, retrospective, observational study, an association between LIPI and the survival of patients with IIPs was evaluated.

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Aim: To determine risk factors associated with hepatocellular carcinoma (HCC) development following direct-acting antiviral (DAA) therapy.

Methods: We enrolled patients with chronic hepatitis C who underwent direct-acting antiviral therapy and achieved sustained virologic response at 12 weeks between 2012 and 2018. Subsequently, patients were followed up.

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  • A phase II study evaluated the effectiveness of oral prednisolone in treating immune-related pneumonitis (irP) in cancer patients after immune checkpoint inhibitors, focusing on the control rate over 6 and 12 weeks.
  • Of 57 enrolled patients, 56 completed the analysis; 91.1% had pneumonitis control at 6 weeks, but this dropped to 57.1% by 12 weeks, with some patients experiencing relapse.
  • Adverse effects were noted in 17.9% of patients, predominantly hyperglycemia, but no treatment-related deaths occurred during the study.
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Background/aim: Maxillary sinus cancer is a relatively rare disease, and treatment is still evolving. We compared the efficacy of superselective intra-arterial infusion of high-dose cisplatin (CDDP) with concomitant radiotherapy (RADPLAT) using three-dimensional conformal radiotherapy (3DCRT) or intensity-modulated radiotherapy (IMRT) and analyzed the relationship between the total radiation dose and the treatment outcome in localized maxillary sinus cancer.

Patients And Methods: We reviewed the cases of 58 patients with localized maxillary sinus cancer treated with RADPLAT at our institution from March 2004 to November 2020.

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Since its introduction in the worldwide medical market, gadoxetic acid has attracted considerable interest. The year 2023 marks the 15th anniversary of the introduction of gadoxetic acid in Japan. Gadoxetic acid-enhanced magnetic resonance imaging (GA-MRI) is the predominantly performed contrast MRI examination for the liver.

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Background: Acute exacerbation of idiopathic interstitial pneumonias (AE-IIPs) induces permanent pulmonary dysfunction and is potentially lethal. The unpredictable occurrence of AE-IIPs remains an important clinical issue in the management of IIPs.

Methods: In this multicentre, retrospective, observational study, a predictive score for AE-IIPs was designed using clinical factors based on multivariate Fine-Gray analysis in patients with IIPs.

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Objectives: To evaluate the feasibility and image quality of intranodal dynamic contrast-enhanced CT lymphangiography (DCCTL) and dynamic contrast-enhanced MR lymphangiography (DCMRL) in microminipigs.

Methods: Our institution's committee for animal research and welfare provided approval. Three microminipigs underwent DCCTL and DCMRL after inguinal lymph node injection of 0.

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MRI is widely used in clinical practice for detecting liver diseases. Since the introduction of gadoxetic acid, MRI has become the most effective modality for the detection and characterization of focal liver lesions. According to previous meta-analyses, the area under the receiver operating characteristic curve (AUROC) was 0.

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  • Tc-pyrophosphate myocardial scintigraphy (Tc-PYP) can help diagnose transthyretin cardiac amyloidosis (ATTR-CA), but false positives can arise from tracer buildup in the blood.
  • A study analyzed 164 patients using Tc-PYP imaging and found that the heart-to-mediastinum (H/M) ratio effectively distinguishes ATTR-CA from non-ATTR-CA cases.
  • The H/M ratio greater than 1.41 demonstrated excellent diagnostic accuracy with 100% sensitivity, suggesting it could serve as a reliable new indicator for ATTR-CA diagnosis.
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Significance: The water and lipid content of normal breast tissue showed mammary gland characteristics with less influence from the chest wall using six-wavelength time-domain diffuse optical spectroscopy (TD-DOS) in a reflectance geometry.

Aim: To determine the depth sensitivity of a six-wavelength TD-DOS system and evaluate whether the optical parameters in normal breast tissue can distinguish dense breasts from non-dense breasts.

Approach: Measurements were performed in normal breast tissue of 37 breast cancer patients.

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Bleeding is a fatal complication after pancreatectomy. Although coil embolization is a widely accepted treatment option, ischemia of the remaining organs should be prevented. This study reports the successful treatment of intra-abdominal hemorrhage following distal pancreatectomy with en bloc celiac axis resection (DP-CAR) using balloon-assisted coil embolization (BACE).

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Evaluation of feasibility and safety of percutaneous radiofrequency ablation using bipolar radiofrequency devices in a prospective multicenter cohort of patients with benign aldosterone-producing adenoma. A total of five institutions participated. CT-guided percutaneous RFA was performed for patients diagnosed as APA.

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Purpose: To define the radiological arterial anatomy in mature microminipigs as a pre-clinical research animal model in interventional radiology.

Materials And Methods: Five female microminipigs (weighing 20.9 ± 2.

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Objectives: To evaluate the diagnostic performance of MRI-based radiomics model for differentiating phyllodes tumors of the breast from fibroadenomas.

Methods: This retrospective study included 88 patients (32 with phyllodes tumors and 56 with fibroadenomas) who underwent MRI. Radiomic features were extracted from T2-weighted image, pre-contrast T1-weighted image, and the first-phase and late-phase dynamic contrast-enhanced MRIs.

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Background: Pancreatic juice is constantly activated by contaminated bile in patients with pancreaticobiliary maljunction (PBM). Here, we report a case of laparoscopic distal pancreatectomy for a patient with PBM and sphincterotomized papilla, resulting in fatal pancreatic fistula.

Case Presentation: A 79-year-old man was diagnosed with pancreatic intraductal papillary mucinous neoplasm and common bile duct stones.

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Objective: To assess the noncontrast two-dimensional single-shot balanced turbo-field-echo magnetic resonance angiography (b-TFE MRA) features of the abdominal aortic aneurysm (AAA) status following endovascular aneurysm repair (EVAR) and evaluate to detect endoleaks (ELs).

Materials And Methods: We examined four aortic stent-grafts in a phantom study to assess the degree of metallic artifacts. We enrolled 46 EVAR-treated patients with AAA and/or common iliac artery aneurysm who underwent both computed tomography angiography (CTA) and b-TFE MRA after EVAR.

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Objectives: The 9th International Forum for Liver Magnetic Resonance Imaging (MRI) was held in Singapore in September 2019, bringing together radiologists and allied specialists to discuss the latest developments in and formulate consensus statements for liver MRI, including the applications of gadoxetic acid-enhanced imaging.

Methods: As at previous Liver Forums, the meeting was held over 2 days. Presentations by the faculty on days 1 and 2 and breakout group discussions on day 1 were followed by delegate voting on consensus statements presented on day 2.

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Purpose: Non-calcified cholesterol stones that are small in size are hard to be depicted on CT or magnetic resonance cholangiopancreatography. This institutional review board (IRB)-approved retrospective in vitro study aims to characterize contrast behaviors of 3 main components of the gallstones, i.e.

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