Publications by authors named "Goshen D Miteu"

Nanoscience and technology have shown promise in revitalizing the agricultural sector and industries. This tool has gained the interest of many researchers as it can be utilized to drive sustainable agriculture by suggesting long-lasting solutions to different problems in the agricultural space. However, there is a paucity of data on its health implications for the environment, plants, animals, and humans.

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Spinocerebellar ataxias (SCAs) are a rare autosomal dominant neurodegenerative disorder. To date, approximately 50 different subtypes of SCAs have been characterized. The prevalent types of SCAs are usually of PolyQ origin, wherein the disease pathology is a consequence of multiple glutamine residues being encoded onto the disease proteins, causing expansions.

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Article Synopsis
  • * Artificial intelligence (AI) is increasingly being used in neurosurgery, enhancing surgeons' capabilities and leading to better patient outcomes and decision-making during procedures.
  • * Recent advancements in AI, machine learning (ML), and deep learning (DL) have significantly improved surgical planning and outcomes, while also helping to reduce complications in patient care.
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Juvenile idiopathic arthritis (JIA) is a chronic clinical condition characterized by arthritic features in children under the age of 16, with at least 6 weeks of active symptoms. The etiology of JIA remains unknown, and it is associated with prolonged synovial inflammation and structural joint damage influenced by environmental and genetic factors. This review aims to enhance the understanding of JIA by comprehensively analyzing relevant literature.

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Article Synopsis
  • Personalized medicine is advancing with RNA therapy, providing new treatment options for cardiovascular diseases (CVD) by targeting the human genome.
  • Current research shows promise in using RNA therapies for diagnosing and preventing heart-related conditions, but only a few treatments are in clinical trials or FDA-approved.
  • Key challenges include delivering drugs effectively to cells, managing immune responses, and ensuring overall safety, which need to be addressed for RNA therapies to progress.
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Coronary Artery Disease (CAD) represents a persistent global health menace, particularly prevalent in Eastern European nations. Often asymptomatic until its advanced stages, CAD can precipitate life-threatening events like myocardial infarction or stroke. While conventional risk factors provide some insight into CAD risk, their predictive accuracy is suboptimal.

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Antimicrobial resistance (AMR) is still a formidable global public health challenge, as microorganisms, including bacteria, viruses, fungi, and parasites, evolve resistance to commonly used drugs, particularly antibiotics. The preservation of last-resort antimicrobials is critical for treating multi-drug-resistant infections; however, their indiscriminate use can exacerbate AMR crisis. This short communication delves into the multifaceted challenges, innovative strategies, and promising future directions to combat AMR effectively.

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Familial hypercholesterolemia (FH) is a hereditary condition caused by mutations in the lipid pathway. The goal in managing FH is to reduce circulating low-density lipoprotein cholesterol and, therefore, reduce the risk of developing atherosclerotic cardiovascular disease (ASCVD). Because FH patients were considered high risk groups due to an increased susceptible for contracting COVID-19 infection, we hypothesized whether the effects of the pandemic hindered access to cardiovascular care.

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The HIV epidemic remains a public health challenge in Nigeria, with about 1.9 million people living with the virus in 2020. Despite progress in controlling the epidemic, challenges remain, including inadequate funding and limited access to prevention and treatment services for key populations.

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