Publications by authors named "Gosala Sarma"

Introduction: The impact of coronavirus disease 2019 (COVID-19) infection on patients with multiple sclerosis (MS) undergoing various immunomodulating therapies can vary. Individuals on B-cell therapy, such as rituximab, may be more susceptible to infection compared to those treated with natalizumab.

Objective: The objective of this study was to determine the incidence and severity of COVID-19 infection in patients receiving rituximab, natalizumab, and healthy controls.

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Abamectin is an insecticidal/miticidal compound derived from the soil bacterium "Streptomyces avermitilis". Abamectin toxicity in humans is very rare. We present a case of acute neurotoxicity induced by Abamectin, showcasing distinctive MRI brain findings in a 33-year-old female who exhibited a favourable recovery with the aid of supportive care.

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Background: Invasive vagal nerve stimulation (iVNS) is a known treatment approach for patients with refractory epilepsy. Transcutaneous auricular vagus nerve stimulation (tVNS) was developed to overcome the side effects and surgical complications of iVNS. tVNS is proven beneficial in refractory epilepsy.

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Background: India has a high burden of stroke, but there are limited data available on the characteristics of patients presenting with stroke in India.

Aims: We aimed to document the clinical characteristics, practice patterns, and outcomes of patients presenting with acute stroke to Indian hospitals.

Methods: A prospective registry study of patients admitted with acute clinical stroke was conducted in 62 centers across different regions in India between 2009 and 2013.

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Article Synopsis
  • - A 62-year-old male in India was diagnosed with Perry syndrome after presenting with severe respiratory issues and neurological symptoms, including seizures and unsteady gait, alongside a family history of similar illnesses.
  • - Extensive tests ruled out various neuromuscular diseases and conditions, leading to the discovery of a specific genetic mutation in the DCTN1 gene related to Perry syndrome, which is a rare and fatal autosomal dominant disorder.
  • - The patient showed some improvement with treatment using Levodopa and neurorehabilitation, but ultimately passed away three years later, emphasizing the importance of considering Perry syndrome in similar clinical cases.
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Background: Essential oils (EOs) with pro-convulsant properties are known to cause seizures and may worsen migraine. Here we report five cases of cluster headache (CH) secondary to the usage of toothpastes containing pro-convulsant EOs.

Methods: Patients were identified from the headache clinics of three tertiary care hospitals in south India.

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Objective: Essential oils are plant-derived oils and are widely used as an over-the-counter remedy for common ailments. Many essential oils are found to have proconvulsant effects. Here we report a small case series of 3 adults with eseential oil-related status epilepticus.

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Background: Acute management of ischemic stroke involves thrombolysis within 4.5 h. For a successful outcome, early recognition of stroke, transportation to the hospital emergency department immediately after stroke, timely imaging, proper diagnosis, and thrombolysis within 4.

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Neuro radiological findings in Dengue encephalitis are non specific. Here we report a case of Dengue encephalitis with transient splenial hyperintensity appearing as dot sign on magnetic resonance imaging of brain.

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