Publications by authors named "Goruntla Narayana"

Purpose: Rational self-medication (SM) practice among healthcare students is essential to promote the safe, effective, and economical use of medicines for self-diagnosed conditions. The study aimed to assess pharmacy students' knowledge, attitude, and practice about responsible self-medication.

Methodology: A cross-sectional online survey was conducted among Ugandan pharmacy students for one month from March 1 to March 31, 2024.

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Background: Globally, many women express the desire to avoid immediate pregnancy for 24 months postdelivery, and only forty percent use contraceptives during this period. There is an enormous demand for postpartum family planning, particularly in developing countries with low- or middle-income grades. Postpartum intrauterine devices such as long-acting reversible contraceptives (LARCs) are among the most effective methods of family planning in the immediate postpartum period, yet their effectiveness is hindered because of a lack of availability and training.

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Background: Infection prevention and control involve health care practitioners, who are saddled with the duty of ensuring implementation of standard preventive measures to prevent healthcare associated infections.

Objectives: To assess the knowledge and predictors of implementation of standard precautions for infection prevention and control among health care practitioners (HCPs).

Material And Method: A questionnaire-based cross-sectional design was employed in assessing HCPs in Uganda in from April - October 2023.

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Background: The COVID-19 pandemic had an enormous impact on people's quality of life worldwide. Appropriate use of facemasks is an important checkpoint in containing the spread of infection, which was believed to provide the desired level of protection and preserve the community. Given the relative novelty of facemask use in the general population, it is imperative to prioritize the promotion of appropriate facemask utilization and identify factors that may contribute to poor adherence.

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Article Synopsis
  • Women living with HIV in rural western Uganda are at a higher risk for cervical cancer, yet the prevalence of cervical cancer screening (CCS) among these women is only 39.1%.
  • The study identified several factors that increase the likelihood of CCS, such as having a post-secondary education, being HIV-positive for four or more years, having multiple children, and attending antenatal and post-natal care.
  • Health belief factors, like perceived risk and worry about developing cervical cancer, significantly influenced adherence to screening practices among the participants.
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Purpose: Rational drug use (RDU) promotes safe, efficient, and cost-effective utilization of medicines in hospital settings. The aim of this study was to assess rational drug use based on the World Health Organization (WHO) and the International Network for Rational Use of Drugs (INRUD) core drug use indicators.

Patients And Methods: This prospective, descriptive, hospital-based cross-sectional study was conducted among patients attending the Outpatient Department of a secondary care hospital located in the Sheema District of Western Uganda.

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Introduction: Vaccine safety is a major barrier to the uptake of the COVID-19 vaccine by pregnant women. To bring confidence among pregnant women towards vaccine intake, there is a need to synthesize evidence on safety profile of vaccination.

Objective: To assess adverse events (AEs) following COVID-19 vaccination among pregnant women.

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Background: Parents are more concerned about the available evidence of the safety, efficacy, and tolerability of the pediatric COVID-19 vaccine.

Aim: To assess the parents' willingness to vaccinate their children against COVID-19 and associate it with health belief model constructs.

Materials And Methods: A countrywide, online, self-administered, cross-sectional survey was conducted from December 15, 2021 to March 8, 2022.

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  • Vaccine hesitancy is identified as a major global public health threat by the WHO, and limited research exists in India that typically focuses on individual vaccines rather than overall hesitancy patterns.
  • A study conducted in a NGO hospital in Andhra Pradesh involved 574 mothers of children under five, assessing vaccine hesitancy through interviews and reviewing vaccination records, with findings showing a hesitancy prevalence of 28.05%.
  • Results indicated that lower parental education and fewer antenatal visits were associated with higher vaccine hesitancy, while higher socioeconomic status and awareness were linked to lower hesitancy rates, highlighting the influence of demographics and WHO-SAGE factors.
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  • Polypharmacy is common in managing conditions like diabetes and depression, with drugs often interacting due to shared metabolic pathways, specifically CYP450 enzymes.
  • This study investigated how trazodone affects the pharmacokinetics and pharmacodynamics of pioglitazone in both normal and diabetic rat models, as well as in rabbits.
  • The results showed that trazodone enhances the hypoglycaemic effects of pioglitazone by altering its metabolism, suggesting careful management when these drugs are used together.
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  • * A total of 2459 participants completed the survey, revealing that major information sources were television (74.5%) and social media (71.0%), with most respondents exhibiting good knowledge (74.7%) and practices (88.1%) toward COVID-19, but only 57.6% had the correct perception.
  • * Findings indicate a need for educational programs to address misconceptions about COVID-19, as factors like age, education level, urban living, and healthcare profession were linked to better knowledge and practices.
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Introduction: Medication nonadherence is the most common issue observed in the management of diabetes because of complex and lifelong therapy. The study aimed to assess the effect of pharmacist-directed counseling and daily text message reminder on medication adherence and clinical profile of patients with type II diabetes.

Materials And Methods: This prospective, open-labeled, randomized control trial was carried out in outpatient medical department of a secondary care referral hospital.

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Introduction: Responsible self-medication plays a vital role in appropriate use of nonprescription drugs which will improve safety and reduces unwanted effects of drugs.

Aim: This study is designed to assess knowledge, attitude, and practice (KAP) toward responsible self-medication among pharmacy students.

Settings And Design: A cross-sectional survey was conducted in pharmacy students of various colleges located in Anantapur district, Andhra Pradesh, India.

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