Publications by authors named "Gorenshtein A"

Objective: It is unknown whether delay in diagnosis affects morbidity reportedly in paraneoplastic syndromes (PNS). We aimed to explore various aspects of PNS, including prevalence, clinical characteristics, diagnostic criteria, and treatment outcomes.

Methods: We studied n-PNS diagnosis between 2016 to 2023, and included only patients with positive onconeural antibodies, who developed cancer, and exhibited a recognizable PNS phenotype.

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Article Synopsis
  • Herpes simplex virus-1 (HSV-1) encephalitis is the most common type of viral encephalitis globally, but there is limited understanding of long-term mortality rates and influencing factors.
  • A retrospective study analyzed data from HSV-positive encephalitis patients over 23 years, finding that 55.31% of HSV-1 patients died during follow-up, with older age and cancer comorbidities significantly increasing mortality risk.
  • Key findings highlighted that older patients had a higher risk of death, and having cancer dramatically impacted mortality, with an optimal age cut-off of 63.29 years identified for predicting outcomes.
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Hyperuricemia is a known predictor of World Health Organization (WHO) Group 1 pulmonary hypertension (PH) (pulmonary arterial hypertension), but its role in excluding PH secondary to chronic lung diseases (WHO Group 3) remains unclear. We retrospectively analyzed data from 323 patients with severe chronic pulmonary diseases who underwent evaluation for lung transplantation at a tertiary medical center between June 2017 and February 2023. We examined the association between hyperuricemia (serum uric acid > 6 mg/dL or > 0.

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  • Female gender significantly increases the risk of long COVID neurological symptoms, with a review identifying higher rates of fatigue, headaches, brain fog, depression, and anosmia in women compared to men.
  • A systematic search yielded 12 studies involving 6,849 patients (3,414 female) and revealed varying risk ratios for these symptoms specific to females.
  • Results indicate that while these neurological symptoms are prevalent, their occurrence tends to decline one year after infection, though more research is needed for long-term data.
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The prognostic significance of pretransplant N-terminal pro-brain (B)-type natriuretic peptide (NT-proBNP) level has not been investigated in lung transplant recipients. The electronic files of 173 patients with chronic lung disease who underwent lung transplantation in 2018-2022 at a tertiary medical center were retrospectively reviewed. Right heart catheterization (RHC) and NT-proBNP determination were performed preoperatively in all cases.

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Individuals suffering from long-COVID can present with "brain fog", which is characterized by a range of cognitive impairments, such as confusion, short-term memory loss, and difficulty concentrating. To date, several potential interventions for brain fog have been considered. Notably, no systematic review has comprehensively discussed the impact of each intervention type on brain fog symptoms.

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The observations conducted by Bielschowski-Gross method and intravital staining with methylene blue after A.S. Dogiel have shown that the receptors with an annular nervous apparatus are located in the muscular sheath, nerve bundles and ganglia of the intermusclar plexus of the oesophagus, stomach and small intertine of birds.

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