Cardiac performance, biomarkers and gene expression studies in previously sedentary men participating in half-marathon training.

Background: The mechanisms through which exercise reduces cardiovascular disease are not fully understood. We used echocardiograms, cardiac biomarkers and gene expression to investigate cardiovascular effects associated with exercise training.

Methods: Nineteen sedentary men (22-37 years) completed a 17-week half-marathon training program.

Journey in antithrombotic strategies for ST-elevation myocardial infarction.

Our understanding and treatment of the ST-elevation myocardial infarction (STEMI) has led to a tremendous improvement in the care and preservation of life affecting millions yearly. As the medical community continues to discover novel strategies in therapeutics and innovations in prevention, it is imperative to understand the scientific journey the treatment of STEMI has traveled. Furthermore, the research pillars that led to our understanding of the current paradigm of STEMI will be highlighted in an effort to illuminate the foundation on which we now stand.