A novel near-infrared nanomaterial with high quantum efficiency and its applications in real time in vivo imaging.

Fluorescence imaging signal is severely limited by the quantum efficiency and emission wavelength. To overcome these challenges, novel NIR-emitting KNdLiF nanoparticles under NIR excitation was introduced as fluorescence imaging probe for the first time. The photostability of KNdLiF nanoparticles in the water, phosphate buffer saline, fetal bovine serum and living mice was investigated.