Effect of Intranasal Mupirocin Prophylaxis on Methicillin-Resistant Staphylococcus aureus Transmission and Invasive Staphylococcal Infections in a Neonatal Intensive Care Unit.

The use of monthly intranasal mupirocin was associated with a significant reduction in the rate of methicillin-resistant Staphylococcus aureus transmission and Staphylococcus aureus invasive infection in a large neonatal intensive care unit. Resistance to mupirocin emerged over time, but it was rare and was not associated with adverse clinical outcomes.Infect Control Hosp Epidemiol 2018;39:741-745.

Nasopharyngeal colonization with heptavalent pneumococcal conjugate vaccine serotypes of Streptococcus pneumoniae with prolonged vaccine dosing intervals.

Introduction: Universal infant heptavalent pneumococcal conjugate vaccine (PCV-7) immunization, dosed near to the originally recommended schedule of a 3-dose series in the first 6 months of life, then a booster between 12 and 15 months, should reduce nasopharyngeal (NP) carriage of Streptococcus pneumoniae (Spn) PCV-7 types. The reduced availability of PCV-7 altered immunization schedules, particularly for third and fourth PCV-7 doses. We evaluated NP colonization in relation to originally recommended intervals and numbers of PCV-7 doses.

Cytomegalovirus seroprevalence among women of childbearing age during a 10-year period.

The incidence of congenital cytomegalovirus (CMV) disease is dependent on the rate of virus acquisition by susceptible women in temporal proximity to pregnancy. Information about serostatus may help to identify high-risk groups and target interventions. Each year from 1991 to 2000, cord blood specimens (surrogates for maternal serum) from 100 consecutive deliveries were obtained at three hospitals.

Antibodies reactive to Rickettsia rickettsii among children living in the southeast and south central regions of the United States.

Background: The reported annual incidence of Rocky Mountain spotted fever in the United States is 2.2 per million, but studies have suggested that human infection with Rickettsia rickettsii may be more common. This study estimated the prevalence of antibodies reactive to R rickettsii among children living in the southeastern and south central United States.