Publications by authors named "Gordon Conklin"

Article Synopsis
  • *This study at the University of Tennessee analyzed MRI data from 2008 to 2021, focusing on non-domestic felids and identifying various brain and spine abnormalities in a group of 50 animals.
  • *Common brain issues included Chiari-like malformation and inflammation, while spinal problems primarily consisted of intervertebral disc disease, highlighting MRI's importance in diagnosing neurological conditions in these animals.
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As gadolinium-based contrast agents are paramagnetic and have T2 shortening effects, they have the potential to adversely affect gradient recalled echo sequences. The aim of this prospective, cross-sectional study was to evaluate the effects of gadolinium administration on T2*-weighted sequence diagnostic quality and signal intensity when imaging the canine brain. A total of 100 dogs underwent brain magnetic resonance imaging (MRI) including pre- and postcontrast T2*-weighted sequences acquired with a delay (Group A) or immediately (Group B) following gadolinium administration.

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Hepatocellular carcinoma is the most common primary hepatic tumor in dogs and is amenable to surgical resection in many cases. Unfortunately, overlap of sonographic findings between benign and malignant hepatic lesions typically requires more invasive diagnostic tests to be performed (e.g.

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Gadoxetate disodium (Gd-EOB-DTPA; gadolinium-ethoxybenzyl-diethylene triamine penta-acetic acid) is a newly developed paramagnetic contrast agent reported to have a high specificity for the hepatobiliary system in humans. The purpose of this prospective study was to describe effects of Gd-EOB-DTPA contrast administration on MRI characteristics of the liver in eight clinically healthy dogs. Precontrast dorsal and transverse T1-weighted spin echo, T2-weighted fast spin echo, and transverse T1-weighted 3D gradient echo (VIBE; volume-interpolated body examination) pulse sequences were acquired for each dog.

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Article Synopsis
  • Motion artifact significantly affects the quality of abdominal MRI in dogs, prompting a study to evaluate how different pulse sequences impact diagnostic quality.
  • Ten normal dogs were scanned using 16 MRI pulse sequences, leading to independent scoring of diagnostic quality by four observers and calculations of signal-to-noise and contrast-to-noise ratios.
  • The top-performing sequence was dorsal T2 turbo spin echo with fat saturation and breath-holding, while the best overall diagnostic sequence for cranial abdomen featured a combination of techniques that offered short acquisition times and comparable quality, recommended for routine use.
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Mast cell tumors (MCT) are the most common cutaneous tumors in dogs. Our purpose was to describe the magnetic resonance (MR) imaging characteristics of cutaneous MCT and to identify imaging characteristics that allow differentiation of metastatic from normal lymph nodes. Eight dogs with a total of nineMCT were imaged as were their presumed draining and associated contralateral lymph nodes.

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Evaluation of the canine temporomandibular joint (TMJ) is important in the clinical diagnosis of animals presenting with dysphagia, malocclusion and jaw pain. In humans, magnetic resonance imaging (MRI) is the modality of choice for evaluation of the TMJ. The objectives of this study were to establish a technical protocol for performing MRI of the canine TMJ and describe the MRI anatomy and appearance of the normal canine TMJ.

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