The psychological impact of undergoing genetic-risk profiling in men with a family history of prostate cancer.

Background: The ability to identify men at genetically high-risk of prostate cancer (PrCa) would enable screening to be targeted at those most in need. This study explored the psychological impact (in terms of general and PrCa-specific worry and risk perceptions) on men with a family history of PrCa, undergoing prostate screening and genetic-risk profiling, within a research study.

Methods: A prospective exploratory approach was adopted, incorporating a sequential mixed-method design.

Is prophylactic Gentamicin associated with acute kidney injury in patients undergoing surgery for fractured neck of femur?

Background: Single dose Gentamicin (240 mg) has been shown to reduce postoperative wound infection in patients with fractured neck of femur when used in a combined antibiotic regimen. However, concerns have arisen about the risk of acute kidney injury (AKI) in these patients.

Objective: To determine if the use of prophylactic Gentamicin is associated with AKI in fractured neck of femur patients.

The effect of care bundle development on surgical site infection after hemiarthroplasty: an 8-year review.

Background: Proximal femoral fracture is the most common reason for emergency orthopedic admission in the United Kingdom with an annual cost of £ 1.7 billion to the National Health Service. Surgical site infection (SSI) after proximal femoral fracture increases patient morbidity and mortality.

A review of 202 periprosthetic fractures--stem revision and allograft improves outcome for type B fractures.

We report a retrospective review of the outcome of treatment of 202 periprosthetic fractures around total hip arthroplasty (THA) from two specialised arthroplasty centres. Fractures were classified according to the Vancouver classification. The aim was to evaluate treatment methods with respect to stem revision and grafting.