Comparative evaluation of antimicrobial and antifungal efficacy of bioactive root-end filling materials: An study.

Context: Microorganisms are the main cause of failure of endodontic treatment. When retreatment fails periapical surgery followed by retrograde filling is done to seal the apex. A root-end filling material should have antimicrobial property as well as bioactive properties necessary for healing, repair, and regeneration of the apex.