The Indian Chronic Kidney Disease (ICKD) study: baseline characteristics.

Background: Chronic kidney disease (CKD) is an important cause of morbidity and mortality worldwide. There is a lack of information on epidemiology and progression of CKD in low-middle income countries. The Indian Chronic Kidney Disease (ICKD) study aims to identify factors that associate with CKD progression, and development of kidney failure and cardiovascular disease (CVD) in Indian patients with CKD.

Prescription Practices in Patients With Mild to Moderate CKD in India.

Introduction: Patients with chronic kidney disease (CKD) require multiple medications. There is no information on prescription patterns or the use of evidence-based therapies for management of CKD from low-middle-income countries. Using baseline data from the Indian CKD (ICKD) cohort, we describe the drug prescription practices in patients with mild to moderate CKD.

A Systematic Study of the Prevalence and Risk Factors of CKD in Uddanam, India.

Introduction: Despite reports of a high prevalence of chronic kidney disease (CKD) from the coastal Uddanam region of Andhra Pradesh, India, there are no accurate data on the distribution of kidney function abnormalities and CKD risk factors in this region.

Methods: A total of 2419 participants were recruited through multistage cluster random sampling from 67 villages. Serum creatinine and urine protein creatinine ratio were measured using validated methodologies.

Nonmedical Factors and Health-Related Quality of Life in CKD in India.

Background And Objectives: Patient-reported outcomes have gained prominence in the management of chronic noncommunicable diseases. Measurement of health-related quality of life is being increasingly incorporated into medical decision making and health care delivery processes.

Design, Setting, Participants, & Measurements: The Indian Chronic Kidney Disease Study is a prospective cohort of participants with mild to moderate CKD.

Non-steroidal anti-inflammatory drug (NSAID) therapy in patients with hypertension, cardiovascular, renal or gastrointestinal comorbidities: joint APAGE/APLAR/APSDE/APSH/APSN/PoA recommendations.

Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly prescribed medications, but they are associated with a number of serious adverse effects, including hypertension, cardiovascular disease, kidney injury and GI complications.

Objective: To develop a set of multidisciplinary recommendations for the safe prescription of NSAIDs.

Methods: Randomised control trials and observational studies published before January 2018 were reviewed, with 329 papers included for the synthesis of evidence-based recommendations.

Getting to know the enemy better-the global burden of chronic kidney disease.

A good understanding of disease burden is the first step in formulating a response to it. Analysis of the Global Burden of Disease 2016 dataset shows an 87% rise in the global burden of chronic kidney disease and a doubling of chronic kidney disease deaths between 1990 and 2016. Countries with a lower level of socioeconomic development and poorer access to quality health care experience a higher chronic kidney disease burden.

Indian chronic kidney disease study: Design and methods.

Aim: The rate and factors that influence progression of chronic kidney disease (CKD) in developing countries like India are unknown. A pan-country prospective, observational cohort study is needed to address these knowledge gaps.

Methods: The Indian Chronic Kidney Disease (ICKD) study will be a cohort study of approximately 5000 patients with mild to moderate CKD presenting to centres that represent different geographical regions in India.

What Are Optimal Blood Pressure Targets for Patients with Hypertension and Chronic Kidney Disease?

To maximize the risk benefit ratio of blood pressure control in people with chronic kidney diseases (CKD), a number of guidelines provide recommendations on optimal blood pressure (BP) targets in CKD. This review examines these guidelines, their supporting evidence base, and generalizability and limitations of current standards of care. Over the years, the BP targets are liberalized.

Epidemiology and risk factors of chronic kidney disease in India - results from the SEEK (Screening and Early Evaluation of Kidney Disease) study.

Background: There is a rising incidence of chronic kidney disease that is likely to pose major problems for both healthcare and the economy in future years. In India, it has been recently estimated that the age-adjusted incidence rate of ESRD to be 229 per million population (pmp), and >100,000 new patients enter renal replacement programs annually.

Methods: We cross-sectionally screened 6120 Indian subjects from 13 academic and private medical centers all over India.