Publications by authors named "Gopal Viswanathan Velmurugan"

Impairment of vascular pathways of cerebral β-amyloid (Aβ) elimination contributes to Alzheimer disease (AD). Vascular damage is commonly associated with diabetes. Here we show in human tissues and AD-model rats that bloodborne islet amyloid polypeptide (amylin) secreted from the pancreas perturbs cerebral Aβ clearance.

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Article Synopsis
  • Toxoplasmosis, caused by Toxoplasma gondii, significantly impacts livestock, particularly sheep and goats, leading to issues like abortion.
  • Researchers amplified specific DNA sequences for key proteins (SAG1 and GRA7) from T. gondii using PCR, then expressed and purified these proteins for further testing.
  • The study demonstrated that using a cocktail of the recombinant proteins improved diagnostic accuracy for caprine toxoplasmosis through ELISA, marking a significant advancement in serological detection methods.
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