Application of artificial neural networks in optimizing the fatty alcohol concentration in the formulation of an O/W emulsion.

The purpose of this study was to optimize the concentration of a fatty alcohol, in addition to internal phase, for formulating a stable O/W emulsion, by using artificial neural networks (ANNs). Predictions from ANNs are accurate and allow quantification of the relative importance of the inputs. Furthermore, by varying the network topology and parameters it was possible to obtain output values that were close to experimental values.

Norfloxacin sesquihydrate.

IN THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND [SYSTEMATIC NAME: 1-ethyl-6-fluoro-4-oxo-7-(piperazin-4-ium-1-yl)-1,4-dihydro-quinoline-3-carboxyl-ate sesquihydrate], C(16)H(18)FN(3)O(3)·1.42H(2)O, N-H⋯O and O-H⋯O hydrogen bonds assemble the mol-ecules in a two-dimensional layered corrugated sheet structure parallel to the b axis. The water mol-ecules are disordered [occupancies 0.

Bis[5-oxo-4,5-dihydro-8H-2-azonia-4,8,9-trizabicyclo[4.3.0]nona-2,6,9(1)-triene] sulfate.

In the crystal structure of the title compound, 2C(5)H(5)N(4)O(+)·SO(4) (2-), N-H⋯O hydrogen bonds assemble the mol-ecules into a two-dimensional network structure parallel to the cb plane. The S atom of the sulfate ion lies on a special position on a twofold axis.

Interaction study of paracetamol with saturated (capric) and unsaturated (oleic) fatty acids.

Interaction study of paracetamol with saturated and unsaturated fatty acids, namely, capric and oleic acid have been performed by using serial dilution method, release behavior, FT-IR, and DSC study. Preliminary investigations by release studies indicated the possibility of interaction between paracetamol and fatty acids. UV-studies failed to detect any interaction between paracetamol and fatty acids.