The surface chemistry of the Fischer-Tropsch catalytic reaction over Co has still several unknows. Here, we report an in-situ X-ray photoelectron spectroscopy study of Co and Co( ), and in-situ high energy surface X-ray diffraction of Co during the Fischer-Tropsch reaction at 0.15 bar - 1 bar and 406 K - 548 K in a H/CO gas mixture.
View Article and Find Full Text PDFThis study explored body image among transgender and nonbinary adults, including their body appreciation, embodiment, general psychological distress, and gender identity-related pride. This study also considered participants' pursuit of gender-affirming surgery and mental health services. This cross-sectional survey examined participants' ( = 214; = 28.
View Article and Find Full Text PDFStudy Design: Scoping review.
Objective: To identify which markers are used as surrogates for malnutrition in metastatic spine disease and which are the most studied outcomes associated with it.
Methods: A scoping review was performed by searching the PubMed/Medline, EMBASE, and Web of Science databases up to July 2022.
Study Design: Narrative Literature review.
Objective: To provide a general overview of important molecular markers and targeted therapies for the most common neoplasms (lung, breast, prostate and melanoma) that metastasize to the spine and offer guidance on how to best incorporate them in the clinical setting.
Methods: A narrative review of the literature was performed using PubMed, Google Scholar, Medline databases, as well as the histology-specific National Comprehensive Cancer Network guidelines to identify relevant articles limited to the English language.
Study Design: Narrative review.
Objectives: This article aims to provide a narrative review of the current state of research for liquid biopsy in spinal tumors and to discuss the potential application of liquid biopsy in the clinical management of patients with spinal tumors.
Methods: A comprehensive review of the literature was performed using PubMed, Google Scholar, Medline, Embase and Cochrane databases, and the review was limited to articles of English language.
Introduction: Secondary spontaneous pneumothorax (SSP) is a medical emergency where the lung collapses in the presence of underlying chronic lung disease. Current international clinical guidelines advise intercostal drain (ICD) insertion for SSP. However, in a previous small study needle aspiration (NA) has been shown to reduce length of hospital stay (LOHS) and reduce complications.
View Article and Find Full Text PDFAdvanced ovarian cancer with peritoneal metastasis is challenging to treat. Limited tumor delivery and penetration of the therapeutics to deep tumor regions are significant barriers to effective treatment. The rising radiopharmaceuticals offer hopes for patients through targeted delivery.
View Article and Find Full Text PDFObjectives: In cancer studies, assessment of patients' physical function can provide insight into cancer-related symptoms and the side effects of treatment. Physical function can be assessed using patient-reported outcome measures (PROMs), which may or may not include a recall period-the amount of time the questionnaire asks the respondent to think back to answer the questions. More understanding is needed about how patients interpret and respond to items posed with different recall periods, and which recall period they actually use.
View Article and Find Full Text PDFPurpose: There is an unmet need for new treatments for many central nervous system tumors. An expanding body of research supports the use of laser interstitial thermal therapy (LITT) in the treatment of gliomas, recurrent brain metastases, and radiation necrosis.
Methods: In this review, we highlight emerging indications for LITT, including its use adjacent to eloquent structures, in the posterior fossa, and for meningioma and tumors of the vertebral column.
J Biomed Mater Res B Appl Biomater
December 2024
Despite high total knee arthroplasty (TKA) survivorship after 10 years (92%-99%), a gap persists where patient satisfaction lags clinical success. Additionally, while cobalt chrome molybdenum (CoCrMo) use decreases in primary total hip arthroplasty, the alloy continues to be widely used in TKA femoral components. In vivo, CoCrMo degradation may be associated with adverse local tissue reactions (ALTR) and compared with the hip, the damage mechanisms that may release metal in the knee and the potential biological effects remain poorly understood.
View Article and Find Full Text PDFBackground: Prognostic indices for patients with brain metastases (BM) are needed to individualize treatment and stratify clinical trials. Two frequently used tools to estimate survival in patients with BM are the recursive partitioning analysis (RPA) and the diagnosis-specific graded prognostic assessment (DS-GPA). Given recent advances in therapies and improved survival for patients with BM, this study aims to validate and analyze these 2 models in a modern cohort.
View Article and Find Full Text PDFModulation of the crystal field (CF) in lanthanide (Ln) complexes can enhance optical and magnetic properties, and large CF splitting can be achieved with low coordination numbers in specific geometries. We previously reported that the homoleptic near-linear Sm complex [Sm{N(SiPr)}] () is oxidized by the 2,2,6,6-tetramethylpiperidinyl-1-oxy (TEMPO) radical to give the heteroleptic, approximately trigonal planar Sm complex, [Sm{N(SiPr)}(TEMPO)] (). Here, we report the synthesis of homologous [Ln{N(SiPr)}(TEMPO)] (; Ln = Tm, Yb) complexes by the oxidation of the parent [Ln{N(SiPr)}] (; Ln = Tm, Yb) with TEMPO; complexes all contain TEMPO anions.
View Article and Find Full Text PDFStudy Design: Retrospective cohort study.
Objective: To investigate the correlation between comorbid chronic obstructive pulmonary disease (COPD), asthma, tobacco use, and the incidence of postoperative hematoma requiring reoperation after anterior cervical discectomy and fusion (ACDF).
Summary Of Background Data: Prior studies have identified general risk factors such as multilevel fusion and coagulopathy.
Study Design: Retrospective cohort study.
Objective: The purpose of this study was to (1) evaluate recent trends in the use of intraoperative neuromonitoring (IONM) for anterior cervical discectomy and fusion (ACDF) in the United States, (2) assess regional variations in the use of IONM, and (3) assess the association between IONM and clinical outcomes.
Summary Of Background Data: IONM is frequently used during anterior cervical procedures to mitigate the risk of neurological injury.
J Biomed Mater Res A
January 2025
Tin-silver (Sn-Ag) has been used as a permanently implanted biomaterial within the Essure female sterilization device and in dental amalgams; however, little data exist for Sn-Ag's corrosion characteristics and/or cellular interactions. In this study, to assess its suitability as a degradable metallic biomaterial, 95-5 wt% Sn-Ag solder was subjected to corrosion testing including open circuit potential (OCP), electrochemical impedance spectroscopy (EIS), and anodic potentiodynamic polarization in phosphate-buffered saline (PBS) and cell culture media (with serum proteins) at room temperature (25°C) and body temperature (37°C). Cell culture studies were also performed.
View Article and Find Full Text PDFTechno-economic analyses offer insights into how industrial cultivated meat (CM) production could achieve price parity with conventional meat. These analyses use scaling practices, data and facility designs for related bioprocessing fields, including large (≥20,000 l) stirred tank bioreactors and suspension-tolerant, continuously available cell lines. This approach is inconsistent with most primary CM literature, which parallels bench-scale tissue engineering.
View Article and Find Full Text PDFTargeted amplicon sequencing (TAS) facilitates the genotyping of forensically informative single nucleotide polymorphisms (SNPs) using massively parallel sequencing (MPS). For human remains identification, where any extracted DNA is likely to be degraded, TAS may succeed when short tandem repeat (STR) profiling using capillary electrophoresis fails. Further, as well as yielding identity information, SNPs can provide information about ancestry, phenotype, kinship and paternal lineage (Y chromosome haplotypes).
View Article and Find Full Text PDFBackground: The use of plate-cage systems in anterior cervical discectomy and fusion (ACDF) has been shown to produce fusion and good clinical outcomes though it has been associated with complications such as dysphagia at higher rates than stand-alone implant devices. This study aimed to assess the incidence of dysphagia and radiographic outcomes in adult patients who have undergone ACDF with interbody spacer with integrated anchor fixation (ISa).
Methods: Patients who underwent index ACDF with a commercially available ISa by a fellowship-trained spine surgeon between January 2018 and December 2021 were retrospectively included.
Background: The current neurosurgical workforce is not large enough to address the significant burden of neurosurgical disease worldwide, and women are under-represented in this surgical specialty. However, trainee opportunities are particularly scarce in lower- and middle-income countries, where the burden of neurosurgical disease is high. Thus, the primary aim of this study was to assess the effects of gender and country on perceived access to neurosurgical research and mentorship opportunities.
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