[Validity of a score of clinical parameters as a screening method in acute bacterial diarrhea in childhood].

We report a prospective study of the cases of acute diarrhea admitted to our pediatric service during one year (n = 172) to elaborate a screening method to identify patients with bacterial diarrhea. A bacterial causative organism was identified in 31.4%.

[Familial childhood cortical hyperostosis].

We present three cases of Caffey's disease, which have been observed in a family and a previous one former generation of the same family. A review of the literature upon family cases is carried out (35 families with 143 patients) prevailing the hypothesis of the type of autosomal dominant trait with incomplete penetrance and variable expressivity. HLA system is studied in such a family without common haplotypes being found and therefore the trait does not seem to be linked to genes of this system.

[Visceral and cutaneous leishmaniasis in Huesca. Epidemiologic aspects].

The authors present a study of twelve children affected with leishmaniasis, observed in the province of Huesca (Spain). Three of the patients presented visceral form and the other nine cutaneous form. The clinical, evolutive and therapeutic aspects of this disease are analyzed, with special reference to the epidemiological aspects, since the incidence has been found to be high in an area in which the disease is not considered endemic.

[Nanism with high values of GH and no generation of somatomedin after hGH (Laron's syndrome). Clinico-biochemical study of 8 cases].

Eight familial cases with Laron type dwarfism (LTD) are presented. An autosomic recessive transmission seems to be possible with clear predominance in females (6/2). This syndrome first described in Jewish people is probably frequent in our country, with clear historic Jewish antecedents in some of our cases.

[Mucolipidosis III. Apropos of a case].

Authors present a case of mucolipidosis III diagnosed in a boy suffering from articular retractions, platyspondylia and a normal mucolysacchariduria. Biochemical characteristics of the lisosomial enzyme, reduced in fibroblasts in culture and increased in biological fluids allow such diagnose. Primary enzyme lack being not yet explained, authors comment upon the hypothesis trying to explain biochemical findings.