Publications by authors named "Gonzalo Guerrero-Perez"
Introduction: We present a rare occurrence of bilateral corneal melting and a left-eye corneal perforation in an oncologic patient undergoing a new biological therapy.
Case Presentation: A 63-year-old male with a two-day history of a painful left red eye and bilateral visual impairment was enrolled in a multicenter phase-II study comparing tobemstomig/RO7247669, a PD1-LAG3 bispecific antibody, with nivolumab. Clinical examination revealed a bilateral central corneal thinning, and corneal OCT imaging indicated a significant stromal thinning of 124 μm in the right eye and a central corneal perforation of 286 μm in the left eye.
Article Synopsis
- The study discusses a case of surgical-induced necrotizing scleritis in an 88-year-old patient who experienced severe pain in one eye following previous eye surgery.
- After ruling out infections and autoimmune diseases, the patient was treated with various medications including corticosteroids and Methotrexate, but did not improve sufficiently.
- Ultimately, a scleral patch graft was performed, along with the initiation of Adalimumab treatment, leading to better management of the condition six months later.