Telepathology Practice in Cancer Diagnosis in Saint Jean de Dieu Hospital - Tanguieta, Benin.

Context.—: Both the incidence of cancer and cancer-related mortality rates are high in sub-Saharan Africa, while resources for diagnosis and management are inadequate. In Benin, there is an extreme shortage of pathology services.

Woven coronary artery anomaly presenting as sudden cardiac death.

Woven coronary artery is a rare anomaly characterized by thin channels arising from the coronary artery and reanastomosing at the distal arterial segment. To our knowledge, no data are available currently on the histologic structure of the woven segment. A 39-year-old man presented with sudden atypical chest pain while he was practicing cycling.

Magnetic Resonance Imaging for the Pre-Surgical Assessment of Endometrial Cancer: Results in a Routine Clinical Setting, Outside Dedicated Trials; a Cross-sectional Study.

Aim: To assess the efficacy of magnetic resonance imaging (MRI) in predicting the surgical stage of endometrial carcinoma as a diagnostic tool, in a routine clinical setting, and not just in dedicated pilot studies or trials.

Materials And Methods: The stage prediction made on MRI, as stated in the Radiology report, was compared with the effective surgical stage registered in the Pathology report. The 2009 International Federation of Gynecology and Obstetrics (FIGO) staging was used.

Exaggerated placental site/placental site trophoblastic tumor: an underestimated risk factor for emergency peripartum hysterectomy.

Objective: To assess the indications and possible underlying causes of emergency peripartum hysterectomy (EPH) at the present hos- pital during the 2001-2011 period.

Materials And Methods: A revision of the charts and pathology reports corresponding to 42,728 parturients.

Results: During the study period, 25 peripartum hysterectomies were performed (0.

The E-Cadherin expression vs. tumor cell proliferation paradox in endometrial cancer.

Background: E-Cadherin is a putative marker of good prognosis in endometrial cancer. Paradoxically, in a previous study of endometrial carcinoma we found that E-Cadherin is significantly co-expressed with molecular markers of proliferation, usually associated with a worse prognosis in most tumor types.

Patients And Methods: The expression of estrogen (ER) and progesterone receptors (PR), Ki67, Human Epidermal Growth Factor Receptor 2 (HER-2, c-ERB-B2), p53 and E-Cadherin was studied by means of immunohistochemistry in 126 endometrial carcinoma samples.

Centrally necrotizing breast carcinoma: a rare histological subtype, which was cause of misdiagnosis in an evident clinical local recurrence.

Centrally necrotizing carcinoma is a rare subtype of breast carcinoma, which is characterized by an extensive central necrotic zone accounting for at least 70% of the cross-sectional area of the neoplasm. This central necrotic zone, in turn, is surrounded by a narrow rim of proliferative viable tumor cells. We report an unusual clinical situation in which a patient whose evident breast mass suggested an ipsilateral local recurrence and for which numerous attempts to confirm the histological diagnosis had failed.

Patient age and biological aggressiveness of endometrial carcinoma.

Background: Advanced age is associated with a significantly worse prognosis of endometrial carcinoma patients. The aim of this study was to test whether age is a poor-risk factor in endometrial carcinoma because tumors arising in older patients are biologically different from those diagnosed in patients of an earlier age.

Materials And Methods: Formalin-fixed, paraffin-embedded samples from 136 previously untreated patients with endometrial carcinoma were studied by means of immunohistochemistry.

Expression of the apoptosis-related genes Bcl-2 and p53 in clinical samples from endometrial carcinoma patients.

Background: Although alterations in the mechanisms of apoptosis are an integral part of the tumor phenotype, their precise role in endometrial carcinoma is still obscure. The aim was to determine whether Bcl-2 plays a similar biological role in endometrial cancer as in breast cancer, endometrial cancer being also a hormone-dependent tumor.

Materials And Methods: The expression of the apoptosis-related Bcl-2 and p53 genes, together with Ki67, E-cadherin, c-erb-B2 and estrogen and progesterone receptors were studied in 136 formalin-fixed, paraffin-embedded endometrial carcinoma samples by means of immunohistochemistry.

[Verrucous carcinoma of the larynx].

The present work shows a retrospective study of 11 cases of verrucous carcinoma of the larynx from data collected at Marqués de Valdecilla Hospital for ten years. All patients were males. Glottis was the most common site involved (10 cases).

[Sphenoidal metastasis of laryngeal carcinoma].

Metastatic tumors to the nose and paranasal sinuses are very uncommon and metastases to the sphenoid sinus are exceedingly rare. The most common tumor sites from which sphenoid metastases arise are the kidney and the lung. Distant metastases from laryngeal carcinoma are rare, the most common sites being the lungs, skeletal system, and liver.

[Cholesterol granuloma of the petrous apex].

Cholesterol granuloma of the petrous apex is an inflammatory granulation tissue response to the presence of cholesterol crystals. It is not generally associated with middle-ear pathology. CT and MRI are fundamental for diagnosis.

Helicobacter pylori in Barrett's esophagus.

Barrett's esophagus is an anatomicoclinical state in which, due to the prolonged action of gastroesophageal reflux, the squamous epithelium is replaced by columnar epithelium. Helicobacter pylori has been implicated in the pathogenesis of various gastrointestinal disorders and has occasionally been observed in Barrett's esophagus. The aim of this study is to determine the incidence of H.

[Morphologic findings in systemic amebiasis. Apropos of 1 case].

Amebiasis is an uncommon infectious disease in our region. We describe the anatomopathologic findings of the autopsy of a patient who died of systemic amebiasis, briefly commenting the anatomo-clinical characteristics of this disease and its diagnosis.

Normal pregnancy and delivery two years after adjuvant chemotherapy for grade III immature ovarian teratoma.

A 27-year-old woman with grade 3 immature teratoma of the ovary was treated with unilateral salpingo-oophorectomy and VAC combination chemotherapy. She received 6 postoperative courses, although initially 12 were planned. Chemotherapy had to be discontinued because of severe bone marrow toxicity.

[Tubal cancer with cervix metastasis].

A case of tubal carcinoma is presented, which was initially misdiagnosed as an endometrial carcinoma. This was due to a superficial metastasis yielding material during the curettage which simulated an anaplastic adenocarcinoma. The difficulty of correctly diagnosing tubal carcinoma preoperatively has been discussed.