Application of a cost-effective methodology for the refurbishment of DOCOMOMO buildings. A case study in Northern Spain.

The energy rehabilitation of listed buildings guaranteeing heritage values but allowing a use that contributes to their conservation, supposes a challenge with the need of a holistic approach. Buildings of the Modern Movement, many of which are registered as DOCOMOMO (DOcumentation and COnservation of buildings, sites and neighbourhoods of the MOdern Movement), are a particular case since many of them are not yet listed or are under unclear requirements. This paper explores the inclusion of a cost-effective methodology as part of the decision-making in the energy rehabilitation of these DOCOMOMO buildings, applying it to the case study of an office building located in the north of Spain.

[Review and update of the criteria for objective cognitive impairment and its involvement in mild cognitive impairment and dementia].

Introduction: The increase in the incidence and prevalence of dementia has changed the research focus towards its early identification. Several constructs have been developed in order to identify individuals with a high risk of developing dementia, with Mild Cognitive Impairment (MCI) being the term most commonly used in the last decades. However, diagnostic criteria for objective cognitive impairment have been modified using different methods and algorithms.

Chikungunya Virus in Febrile Humans and Aedes aegypti Mosquitoes, Yucatan, Mexico.

Chikungunya virus (CHIKV) was isolated from 12 febrile humans in Yucatan, Mexico, in 2015. One patient was co-infected with dengue virus type 1. Two additional CHIKV isolates were obtained from Aedes aegypti mosquitoes collected in the homes of patients.

Dengue Patients Treated with Doxycycline Showed Lower Mortality Associated to a Reduction in IL-6 and TNF Levels.

Objective: To determine the effect of doxycycline treatment on cytokine levels, including tumor necrosis factor (TNF) and interleukin 6 (IL-6), and mortality in dengue patients at high risk of complication.

Methods: A group of dengue hemorrhagic fever patients (n=231) were randomized to receive either standard supportive care or supportive care in addition to oral doxycycline twice daily for 7 days. Dengue virus infection was confirmed by PCR using multiple primers.

Collagen I confers gamma radiation resistance.

The effect of collagen on the response of somatomammotroph tumor cells (GH3) to gamma, radiation therapy was studied in vitro. After incubating confluent GH3 cell monolayers in a serum-free, maintaining medium, either with or without collagen, the monolayers were irradiated with 137Cs, gamma radiation. Collagen reduces cell mortality via ERK1/2 activation, abolishing gamma radiation, cell death, and promotes cell invasion when acting in synergy with collagen and in association with the, MAPK/ERK1/2 signaling pathway activation.

[CCR5-Δ32 allele involvement in the clinical evolution of HIV1+ patients in Yucatán, Mexico].

Objective: CCR5-Δ32 allele frequency needs to be identified in HIV+ patients and exposed seronegative individuals in Yucatan, Mexico, to understand this mutation's relationship to infection and disease progression.

Material And Methods: A total of 355 samples were analyzed: 62 from HIV+ patients, 51 from exposed seronegative individuals and 242 from general population. Infected patients were subdivided into a) normal progressors n= 49; b) slow progressors n= 10, and c) non-progressors n= 3.

[Prevalence of iron-deficient anemia in rural pregnant women in Valldolid, Yucatan, Mexico].

Objective: To determine the prevalence of iron-deficiency anaemia among rural pregnant women in Valladolid, Yucatan, Mexico.

Materials And Methods: A descriptive study was carried out from March to May 2006. A clinical-epidemiological survey, a complete blood count test and a ferritin test were applied to a non-random sample conformed by 51 rural pregnant women.

[Antibiotic resistance of Escherichia coli from community-acquired urinary tract infections. What antimicrobial to use?].

Objective: Determine antibiotic resistance of community-acquired uropathogen Escherichia coli and infer therapeutic options.

Material And Methods: E. coli strains isolated from urine during a one-year period were studied.

Dengue virus-infected Aedes aegypti in the home environment.

We determined abundance of Aedes aegypti mosquitoes and presence of dengue virus (DENV) in females collected from premises of laboratory-confirmed dengue patients over a 12-month period (March 2007 to February 2008) in Merida, Mexico. Backpack aspiration from 880 premises produced 1,836 females and 1,292 males indoors (predominantly from bedrooms) and 102 females and 108 males from patios/backyards. The mean weekly indoor catch rate per home peaked at 7.

Ag nanoparticle effects on the thermoluminescent properties of monoclinic ZrO(2) exposed to ultraviolet and gamma radiation.

The goal of this work was to analyse ZrO(2) in the pure state and when doped with Ag nanoparticles, by electron microscopy, x-ray diffraction and thermoluminescence methods. According to the results obtained, Ag nanoparticles did not modify the morphology or the crystalline structure of the ZrO(2). The thermoluminescent (TL) response of pure ZrO(2) showed two peaks, one at 334 K and the other at 417 K, when it was exposed to ultraviolet (UV) radiation, and at 342 and 397 K when gamma radiation was used.

[Hyperlipidemia and glucose intolerance in patients with HIV infection receiving antiretroviral therapy].

Objective: To determine the prevalence of secondary effects on lipid metabolism as a result of highly active antiretroviral therapy (HAART), as well as the impact of different types of antiretroviral regimens on lipids and glucose in a group of patients in Yucatan, Mexico.

Material And Methods: A cross-sectional study was conducted. A questionnaire created for this study was administered to each patient and total cholesterol, triglycerides and fasting glucose values were determined.

Co-infection by the human T-cell lymphotropic virus type II in patients infected by the human immunodeficiency virus in Yucatan, Mexico.

Background: The HTLV-II infection has been reported in patients with HIV infection as often in asymptomatic as those with acquired immunodeficiency syndrome (AIDS). The aim of this study was to determine the prevalence of HTLV-II infection in a group of patients infected by HIV in our region, as well as determining the risk factors associated with HTLV-II transmission in this group of patients and its impact on the clinical course of HIV infection.

Methods: A cross-sectional study was carried out to determine the prevalence of co-infection of HIV-1 and HTLV-II among 192 patients from Yucatán, México.

HIV-encephalopathy as initial manifestation of acquired immunodeficiency syndrome in Yucatán State, Mexico.

Background: The frequency of neurologic manifestations of the central nervous system (CNS) as a defining disease of acquired immunodeficiency syndrome (AIDS) (neurologic manifestation defining disease [NMDD-AIDS]) varies according to geographic region. The aim of this study was to determine its prevalence among patients with AIDS diagnosed in the state of Yucatán, Mexico.

Methods: We carried out a retrospective study in which AIDS cases reported at the Health Department in the state of Yucatán, Mexico from January 1983 to July 2001 were analyzed.

Frequency of antibodies against the hepatitis C virus in patients with hepatic cirrhosis in Yucatan, Mexico.

Objective: To report the prevalence of antibodies against the hepatitis C virus (anti-HCV) in a group of patients with hepatic cirrhosis (HC).

Material And Methods: A prospective transversal and descriptive study was carried out from March 1998 to May 1999. Study subjects were 153 patients; 117 (76%) male and 36 (24%) female, diagnosed with HC.

Intercomparison of absorbed dose to water measurements for 60Co gamma rays using Fricke, alanine and radiochromic dye film dosimetry.

Measurements of absorbed dose at 5 cm depth in a 30 x 30 x 30 cm3 water phantom have been performed using three independent dosimetric techniques: Fricke, alanine and radiochromic dye film (GafChromic HD-810). The measurements were carried out in the secondary standard dosimetry laboratory at ININ Mexico using a collimated 60Co gamma source with a radiation field of 10 x 10 cm2 at the phantom front surface. The source to phantom distance was set at 100 cm.