Publications by authors named "Gonzalez-Canete M"
Pathogenic sequence changes in mitochondrial DNA (mtDNA) are one of the most common causes of genetic hearing loss. We report an infant with palmoplantar hyperkeratosis, extrapalmoplantar cutaneous features and mitochondrial sensorineural hearing loss caused by the previously reported pathogenic NC_012920:m.7445A > G sequence change in the mitochondrial gene COX1 (COX1, MT-CO1).
View Article and Find Full Text PDFWith the introduction of large-scale COVID-19 vaccination programs, a variety of cutaneous manifestations have been described. We present two girls (ages 12 and 5 years) who developed erythema nodosum (EN) 3 and 14 days after Pfizer-BioNTech COVID-19 vaccination, respectively. While EN after COVID-19 vaccination has been reported in adults, it is can also occur in children.
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- Apremilast is an oral medication used to treat psoriasis, psoriatic arthritis, and oral ulcers in Behçet's disease, with a study analyzing its use among 41 patients in relation to biological treatments.
- The majority of patients (85.4%) took apremilast for psoriasis, often due to inadequate results from previous treatments, and the medication's continuation wasn't significantly affected by prior biologic use.
- The main reason for stopping apremilast was lack of effective disease control (60.0%), with many patients transitioning to biologic therapies thereafter.