Serum inhibin is inversely correlated with serum FSH levels in adult men.

Serum inhibin, FSH, and testosterone levels were measured by radioimmunoassay in 36 normal human males, aged 8 to 63 years. Inhibin and FSH levels rose during 8 to 17 years to reach adult values. At these ages there is a significant direct linear correlation between serum FSH and inhibin levels (r = 0.

In vitro synthesis and release of inhibin in response to FSH stimulation by isolated segments of seminiferous tubules from normal adult male rats.

The production of inhibin by isolated segments of seminiferous tubules from adult male rats cultured in vitro was investigated using a heterologous specific radioimmunoassay. Increasing lengths of tubules (5, 10, 20 and 40 cm) maintained in culture for 4 or 5 days produced increasing amounts of inhibin in vitro. A dose-dependent increase in inhibin production was observed after stimulation with ovine follicle-stimulating hormone (FSH)-s17 (0.

Corrected seminal fructose levels: index of secretory activity of seminal vesicles.

Seminal fructose, sperm count, and sperm motility were measured in 340 men attending an infertility clinic. Seminal fructose correlates negatively with sperm count but not with sperm motility. The best correlation between sperm count and seminal fructose was obtained using the logarithm (log) of sperm count.

Midline "nonhealing" granuloma.

Destructive processes of the midface can occur in a wide variety of diseases. Intrinsic in consideration of these is a cluster of lesions, including Wegener's granulomatosis (WG), idiopathic midline granuloma (IMG), polymorphic reticulosis (PR), and lymphoma. Although there is still confusion as to whether the latter three represent a spectrum of the same malignant process, there is general agreement that WG is a separate entity on the basis of clinical presentation and therapeutic response.

Acetylcholinesterase of Schistosoma mansoni. Molecular forms of the solubilized enzyme.

Several molecular forms of acetylcholinesterase were obtained from Schistosoma mansoni homogenates by extraction in either low-salt buffer, high-salt buffer or detergent buffer. The low-salt soluble form amounts to 25% of the total activity. By contrast, the extract obtained in the presence of Triton X-100 possessed almost almost 3-fold higher enzymatic activity, most of it (86%) being retained in the soluble extract (100 000 X g).

Alterations in high-affinity binding characteristics and levels of opioids in invertebrate ganglia during aging: evidence for an opioid compensatory mechanism.

In Mytilus and Leucophaea the high-affinity binding site density is significantly lower in old animals than in young animals, whereas the low-affinity site density remains unchanged. In Mytilus the estimated met-enkephalin and met-enkephalin-Arg6-Phe7 levels are significantly higher in old than in young animals. In Leucophaea only the met-enkephalin level can be determined, and it is also higher in old animals.

Secular change in growth of native children and adolescents at high altitude Huancayo, Peru (3,280 meters).

Stature and weight of native children, adolescents, and adults at Huancayo , Peru (3,280 meters), were measured in 1977, 1978, and 1982 and compared with mean statures and weights reported in previous studies. The data indicate that in Huancayo there has been a secular increment in child stature, sitting height, and weight from 1937 to 1978-1982. The observed changes in stature are related to a proportionally greater increment in leg length relative to trunk length.

A demonstration that 5-hydroxytryptamine administered peripherally can affect sexual behavior in male rats.

In the male rat, subcutaneous injections for 7 days of 20 mg/Kg B.W./day of 5-hydroxytryptamine creatinin sulphate (5-HT), caused remarkable inhibitory effects on sexual behavior.

Secular change in growth of native children and adolescents at high altitude I. Puno, Peru (3800 meters).

A cross sectional sample of 969 native males from Puno (Peru), altitude 3800 m, ranging in age from 7-20 years, and studied for body height, weight, sitting height, leg length, and chest circumference in 1980, were compared, from the point of view of secular trend, with another cross sectional sample of 992 native males from the same place, which were investigated in 1945. In addition, similar observations were carried out in 1980, in a group of 112 females. The data indicate that in Puno there has been no secular increment in the adult body size.