Publications by authors named "Gonul Seyda Seydel"
Background: Inflammation plays a crucial role in the progression of acute coronary syndrome.
Aims: The aim of this study was to investigate the relationship between the SYNTAX score and new inflammatory markers including albumin-globulin ratio (AGR), C-reactive protein-to-albumin ratio (CAR), fibrinogen-to-albumin ratio (FAR), neutrophil-to-albumin ratio (NAR), and neutrophil percentage-to-albumin ratio (NPAR) in STEMI and NSTEMI patients.
Methods: The study involved 53 STEMI and 64 NSTEMI patients, and each patient group was evaluated separately.
Article Synopsis
- Gelsolin (GSN) has two forms: plasma (pGSN) and cytosolic (cGSN), which are linked to various diseases.
- The study examined how chronic sustained hypoxia (CSH) impacts GSN levels and HIF-1 in rats, alongside measuring apoptosis and redox status.
- Findings revealed that HIF-1α significantly increased in severe hypoxia, while pGSN decreased in both plasma and tissue, and cGSN levels increased in lung tissue, indicating a potential protective mechanism against cell damage.
Hemoglobinopathies are one of the most widespread hereditary disorders in Turkey. The present study aimed to determine the prevalence of hemoglobinopathies in the Nigde province of Turkey. This study was conducted with 2013 individuals who applied for the premarital screening, between January 2019 and December 2021.
View Article and Find Full Text PDFBackground: This study aims to compare serum HMGB-1, 3-nitrotyrosine (3-NT), TAS, TOS, and OSI levels in Wettype Age-Related Macular Degeneration (wAMD) patients and healthy controls to determine the correlation of these parameters with each other.
Methods: Thirty patients with Wet-type Age-Related Macular Degeneration (wAMD) and 27 healthy adults, as controls were enrolled in the study. We determined the TAS and TOS levels in serum samples of both groups using commercial kits on a microplate reader.