Nomogram for hepatic steatosis: A simple and economical diagnostic tool for massive screening.

Aim: To establish a simple economical diagnostic tool for prediction of hepatic steatosis in patients with hepatitis B virus (HBV) infection.

Methods: From January 2006 to January 2015,a total of 1325 consecutive subjects who underwent liver biopsy were enrolled. According to the results of multivariate logistic regression analysis, a new nomogram was conducted.

Thyroid function is associated with non-alcoholic fatty liver disease in chronic hepatitis B-infected subjects.

Background And Aims: Associations between thyroid function and non-alcoholic fatty liver disease (NAFLD) are unknown in chronic hepatitis B (CHB)-infected patients. Thus, the aim of the study was to investigate the prevalence of thyroid dysfunction and its relationship with NAFLD in CHB.

Methods: Consecutive naive CHB infected patients that had undergone liver biopsy and serum thyroid function tests between January 2007 and December 2011 were retrospective analyzed.

Hepatic steatosis is highly prevalent in hepatitis B patients and negatively associated with virological factors.

Background And Aims: The interaction between hepatitis B virus (HBV) infection and hepatic steatosis remains unclear. We aimed to explore the trend of prevalence of hepatic steatosis and its relationship with virological factors in HBV infected patients.

Methods: Consecutive untreated patients with chronic HBV infection at Shunde Hospital between 2002 and 2011 were included.

[Expression and clinical significance of HBsAg and HBcAg in hepatocytes in chronic hepatitis B].

Objective: To study the expression of HBsAg and HBcAg in hepatocytes in CHB patients, and analyze the correlation among the expression of HBsAg and HBcAg, the quantity of HBV DNA in serum, the pathology of liver tissue and the clinical manifestation.

Methods: Quantitative polymerase chain reaction was used to assay the quantity of HBV DNA in serum in 351 CHB patients. Furthermore pathological diagnosis was performed using liver biopsy to assay the expression of HBsAg and HBcAg in hepatocytes by an immunohistochemical staining technique.