Publications by authors named "Gong-Jie Li"

This study's aim was to investigate functional brain connectivity changes among patients with moyamoya disease (MMD) with limb paresthesia, using functional connectivity analysis based on resting-state functional magnetic resonance imaging (rs-fMRI). A total of 181 patients with MMD were enrolled, including 57 with left limb paresthesia (MLP group), 61 with right limb paresthesia (MRP group), and 63 without paresthesia (MWP group). Encephaloduroarteriosynangiosis (EDAS) was performed in 20 of the 57 patients with left limb paresthesia and 15 of the 61 patients with right limb paresthesia.

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Purpose: To investigate the structural and network topological changes in the white matter (WM) in MMD patients with limb paresthesia by performing diffusion kurtosis imaging (DKI).

Materials And Methods: A total of 151 MMD patients, including 46 with left-limb paresthesia (MLP), 52 with right-limb paresthesia (MRP), and 53 without paresthesia (MWP), and 28 healthy controls (HCs) underwent whole-brain DKI, while the surgical patients were reexamined 3-4 months after revascularization. The data were preprocessed to calculate the fractional anisotropy (FA) and mean kurtosis (MK) values.

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Objective: The objective of this study was to investigate the changes in the blood oxygen level-dependent (BOLD) response in the ipsilateral primary somatosensory cortex (SI) and thalamus of patients with moyamoya disease (MMD) during sensory stimulation.

Methods: Sixty-four MMD patients, and 15 healthy volunteers were enrolled. Thirty-three MMD patients exhibited paroxysmal numbness or hypoesthesia in the unilateral limbs.

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Background: The usefulness of 3D deep learning-based classification of breast cancer and malignancy localization from MRI has been reported. This work can potentially be very useful in the clinical domain and aid radiologists in breast cancer diagnosis.

Purpose: To evaluate the efficacy of 3D deep convolutional neural network (CNN) for diagnosing breast cancer and localizing the lesions at dynamic contrast enhanced (DCE) MRI data in a weakly supervised manner.

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Background: The metastasis of axillary lymph node (ALNs) is a critical step in the initial cancer staging of newly diagnosed breast cancer (BC) patients. Various imaging modalities can enhance the sensitivity of clinical examination in assessing the ALN status.

Patients And Methods: We enrolled 135 patients with BC, confirmed via histopathology, including 4 bilateral BC cases.

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Purpose: To characterize the changes in cortical thickness of adult patients with moyamoya disease (MMD).

Methods: 60 patients with MMD and 60 age and sex-matched healthy volunteers were recruited. Structural images were acquired by MRI.

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Objective: The aim of this study was to explore the response to neoadjuvant chemotherapy (NAC) in nonconcentric shrinkage pattern of breast cancer (BC) patients using H-magnetic resonance spectroscopy.

Methods: Twenty-five BC patients were the study cohort. All patients received AT-based regimen as first-line treatment.

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Background And Purpose: For Moyamoya disease (MMD) patients, accurate hemodynamic assessment is critical for treatment selection and efficacy assessment. This study aims to investigate the clinical value of mTI-ASL in assessing the cerebral hemodynamics of MMD patients before and after revascularization, relative to DSC-MRI.

Materials And Methods: Forty-one MMD patients underwent mTI-ASL and DSC-MRI during blood perfusion.

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Purpose: To assess the severity of cerebral hemodynamic impairment and hemodynamic improvements, after revascularization in moyamoya disease (MMD) by means of blood-oxygen-level dependent functional magnetic resonance imaging (BOLD-fMRI).

Materials And Methods: BOLD-fMRI with median nerve electrical stimulation based on echo planar imaging was performed in 73 volunteers with MMD and 15 healthy volunteers using a 3.0 Tesla MRI scanner.

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Objective: We aimed to study the value of blood oxygen level-dependent functional magnetic resonance imaging (BOLD-fMRI) in assessing cerebral hemodynamic changes for moyamoya disease (MMD).

Methods: We recruited 15 healthy volunteers, 15 patients with MMD without dyskinesia, and 30 patients with MMD who experienced paroxysmal limb dyskinesia. The BOLD-fMRI scans were obtained during grasping motions of the left or right hand.

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Introduction: The relationship between quantitative parameters of contrast-enhanced computed tomography (CT) and non-small cell lung cancer (NSCLC) progression remains controversial. We aimed to explore the usefulness of contrast-enhanced spiral CT scanning for confirming the time of tumour progression before targeted treatment of NSCLC.

Methods: Contrast-enhanced spiral CT scanning was performed on 33 NSCLC patients with a biopsy-proven diagnosis of NSCLC.

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Article Synopsis
  • This study evaluates how effective clinical examination, ultrasound, and mammography are in assessing the response to neoadjuvant chemotherapy for breast cancer in 141 patients.
  • The findings reveal high rates of misjudgment in tumor response, with clinical exams and ultrasounds frequently overestimating tumor size and nodal status.
  • The authors recommend that clinicians should rely on pathological evaluations, like needle puncture or sentinel lymph node biopsy, to better determine node status and avoid false assessments during treatment.
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