Publications by authors named "Gong-Ji Wu"
Article Synopsis
- * CT frogs show a significant decrease in the expression of their identical ND5 genes when exposed to lower temperatures, while TT frogs maintain stable expression levels in their different ND5 genes.
- * Overall, mitochondrial gene expression patterns vary by organ, with the brain showing the most significant changes under low temperatures, followed by the liver and kidney for both subspecies.
Use of Low-Dose Recombinant Factor Ⅶa for Uncontrolled Perioperative Bleeding.
Dose Response
November 2020
Background: Recombinant activated factor VIIa (rFVIIa) is a prohemostatic agent initially approved for use in hemophilia patients and has also been used for a diverse range of off-label indications in the context of massive uncontrolled blood loss; however, no convincing evidence exists regarding the optimal dose of rFVIIa to treat uncontrolled bleeding in surgical patients.
Aim: To evaluate the effects and safety of a very low dose of rFⅦa in patients with uncontrolled perioperative bleeding in the surgical intensive care unit (ICU).
Methods: 55 patients from Beijing Hospital, who received rFⅦa between July 2004 and November 2018 for uncontrolled perioperative bleeding were included.