Clinical practice guideline for transurethral plasmakinetic resection of prostate for benign prostatic hyperplasia (2021 Edition).

Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, and has become an important global burden of disease. Transurethral plasmakinetic resection of prostate (TUPKP) is one of the foremost surgical procedures for the treatment of BPH. It has become well established in clinical practice with good efficacy and safety.

Identification of a ten-long noncoding RNA signature for predicting the survival and immune status of patients with bladder urothelial carcinoma based on the GEO database: a superior machine learning model.

Bladder urothelial carcinoma (BLCA) is recognized to be immunogenic and tumorigenic. This study identified a novel long noncoding RNA (lncRNA) signature for predicting survival for patients with BLCA. A univariate Cox regression model and the random survival forest-variable hunting (RSF-VH) algorithm were employed to achieve variable selection.

The prognostic value of miRNA-18a-5p in clear cell renal cell carcinoma and its function via the miRNA-18a-5p/HIF1A/PVT1 pathway.

Clear cell renal cell carcinoma(ccRCC) is the most common type of renal cell carcinoma. While it is curable when detected at an early stage, some patients presented with advanced disease have poor prognosis. We aimed to identify key genes and miRNAs associated with clinical prognosis in ccRCC.

[Application of Chinese medicine quality constant in grades evaluation of Moutan Cortex].

There are more and more literature reports about the application of Chinese medicine quality constant in the grading evaluation of Chinese medicine decoction pieces. Chinese medicine quality constant has particularly prominent advantages in comprehensive quantification,so it has become a new method and mode for grading Chinese medicine decoction pieces,highly recognized by the academic circle. In order to determine the effect of Chinese medicine quality constant,a method of grades evaluation for Moutan cortex was established in this paper.

A five-gene signature may predict sunitinib sensitivity and serve as prognostic biomarkers for renal cell carcinoma.

Sunitinib resistance is, nowadays, the major challenge for advanced renal cell carcinoma patients. Illuminating the potential mechanisms and exploring effective strategies to overcome sunitinib resistance are highly desired. We constructed a reliable gene signature which may function as biomarkers for prediction of sunitinib sensitivity and clinical prognosis.

[Explore a method for formulation of limit standard of toxic components in traditional Chinese medicine:aristolochic acid as a case study].

It is urgent to establish the limit standard of toxic components of Chinese herbal medicine, since the safety of traditional Chinese medicine (TCM) has attracted more and more attention.This paper analyzes the present situation and problems in the study of the limit standard of toxic components of Chinese herbal medicine. In addition, the current methods for setting the limit standards of toxic ingredients of TCM are reviewed in this paper, and we also propose a theoretical calculation method for setting the limit standards of toxic ingredients of TCM.

The Dome Wall of Bladder Acts as a Pacemaker Site in Detrusor Instability in Rats.

BACKGROUND The aim of this study was to confirm that the interstitial cells of Cajal (ICCs) in the dome wall of the bladder are pacemaker cells, and that the dome wall of the bladder acts as a pacemaker site in the detrusor instability (DI) rat model. MATERIAL AND METHODS The model of DI in Wistar rats was established and urodynamic studies measuring the bladder volume and pressure were performed. The detrusor excitability was investigated using the amplitude and frequency of phasic contraction of strips.

Highly Sensitive and Selective Turn-on Fluorescent Probe for Hg Based on Rhodamine 6G-Thiourea Conjugate.

An easily available novel fluorescent probe based on rhodamine 6G-thiourea conjugate (RGTU) has been synthesized. Upon mixed with Hg in CHCN-HO (1:9, v/v), the dramatic enhancement of fluorescence intensity as well as the color change of the solution were observed. The presence of common coexisting alkali, alkaline earth, and transition metal ions showed small or no interference with the detection of Hg.

[Comparative analysis of trace elements in five marine-derived shell TCM using multivariate statistical analysis].

A comparable study were carried out by determination of trace elements on five marine-derived shell traditional Chinese medicine (TCM) (Ostreae Concha, Haliotidis Concha, Margaritifera Concha, Meretricis Concha, and Arcae Concha), which were recorded in the Chinese Pharmacopoeia (2010 version). Seven trace elements in 51 batches of this type of shell TCM were analyzed by Inductively Coupled Plasma Mass Spectrometry (ICP-MS), combined with principal component analysis (PCA) methods. The content of element Se, which exhibited significant differences among different drugs, could be used as a key element to distinguish this type of drugs.

[Combination of the ureteral dilation catheter and balloon catheter under the ureteroscope in the treatment of male urethral stricture].

Objective: To investigate the clinical application of the ureteral dilation catheter combined with the balloon catheter under the ureteroscope in the treatment of urethral stricture in men.

Methods: Under the ureteroscope, 45 male patients with urethral stricture received placement of a zebra guide wire through the strictured urethra into the bladder and then a ureteral dilation catheter along the guide wire, followed by dilation of the urethra from F8 initially to F14 and F16. Again, the ureteroscope was used to determine the length of the strictured urethra, its distance to the external urethral orifice, and whether it was normally located.

[Study on an Algorithm for Near Infrared Singular Sample Identification Based on Strong Influence Degree].

Correcting sample selection and elimination of singular sample is very important for the quantitative and qualitative modeling of near infrared spectroscopy. However, methods for identification of singular sample available are generally based on data center estimates which require an experience decision threshold, this largely limit its recognition accuracy and practicability. Aiming at the low accuracy of the existing methods of singular sample recognition problem, this paper improves the existing metric-Leverage value and presents a new algorithm for near infrared singular sample identification based on strong influence degree.

A Sensitive and Selective Fluorescent Coumarin-Based Probe for Detection of Hypochlorite ion and its Application to Cellular Imaging.

Selective, sensitive fluorescent probes for ClO(-) are desirable due to the importance of ClO(-) in biological processes. Herein, a readily available turn-off fluorescent probe for ClO(-) is reported, which displays highly selectivity and sensitivity over other common anions and reactive oxygen/nitrogen. Moreover, it is able to detect ClO(-) in Ramos cells via cellular imaging.

[Identification of marine-derived shell TCM by near infrared spectroscopy].

The identification of five marine-derived shell traditional Chinese medicine (TCM) recorded in the Chinese Pharmacopoeia were studied. Using near infrared technology (NIR) combined with principal component analysis (PCA) methods, Ostreae Concha, Haliotidis Concha, and Margaritifera Concha could be efficiently distinguished from Meretricis Concha together with Arcae Concha. In the first principal components, Ostreae Concha exhibited obvious differences with high loadings in 4 236, 5 263, 7 142 cm(-1) concerning to the contents of CaCO3 and H2O in the samples.

[Research on monitoring land subsidence in Beijing plain area using PS-InSAR technology].

In the present paper, the authors use permanent scatterers synthetic aperture radar interferometry (PS-InSAR) technique and 29 acquisitions by Envisat during 2003 to 2009 to monitor and analyze the spatial-temporal distribution and mechanism characterize of land subsidence in Beijing plain area. The results show that subsidence bowls have been bounded together in Beijing plain area, which covers Chaoyang, Changping, Shunyi and Tongzhou area, and the range of subsidence has an eastward trend. The most serious regional subsidence is mainly distributed by the quaternary depression in Beijing plain area.

Early channel transurethral resection of the prostate for patients with urinary retention after brachytherapy.

Objective: It is recommended that transurethral resection of the prostate (TURP) after brachytherapy should not be performed at an early stage after implantation. Herein we report our experiences and the results of channel TURP (cTURP) within six months post-implant for patients with refractory urinary retention.

Methods: One hundred and ninety patients with localized prostate cancer of clinical stages T1c to T2c were treated by brachytherapy as monotherapy at our institution from February 2009 to July 2013.

[Spatial-temporal evolution characterization of land subsidence by multi-temporal InSAR method and GIS technology].

Long-term over-exploitation of underground resources, and static and dynamic load increase year by year influence the occurrence and development of regional land subsidence to a certain extent. Choosing 29 scenes Envisat ASAR images covering plain area of Beijing, China, the present paper used the multi-temporal InSAR method incorporating both persistent scatterer and small baseline approaches, and obtained monitoring information of regional land subsidence. Under different situation of space development and utilization, the authors chose five typical settlement areas; With classified information of land-use, multi-spectral remote sensing image, and geological data, and adopting GIS spatial analysis methods, the authors analyzed the time series evolution characteristics of uneven settlement.

[The impact of load density differences on land subsidence based on build-up index and PS-InSAR technology].

The excessive mining for underground water is the main reason inducing the land subsidence in Beijing, while, increasing of load brought by the urban construction aggravate the local land subsidence in a certain degree. As an international metropolis, the problems of land subsidence that caused by urban construction are becoming increasingly highlights, so revealing the relationship between regional load increase and the response of land subsidence also becomes one of the key problems in the land subsidence research field. In order to analyze the relationship between the load changes in construction and the land subsidence quantitatively, the present study selected the TM remote sensing image covering Beijing plain and used Erdas Modeler tool to invert the index based on building site (IBI), acquired the spatial and temporal change information in research area further; Based on results monitored by PS-InSAR (permanent scatterer interferometry) and IBI index method, and combined with the GIS spatial analysis method in the view of pixels in different scales, this paper analyzes the correlation between typical area load change and land subsidence, The conclusions show that there is a positive correlation between the density of load and the homogeneity of subsidence, especially in area which has a high sedimentation rate.

[Study on reflectance spectra morphological character of the hyperspectral mixed pixels at different component proportion].

Under the experimental condition, the hyperspectral reflectance spectra of the mixed pixel of lotus and water body were acquired using the multi-angles dichotic reflex platform and ASD spectrum instrument. The reflectance spectral morphological character index variation of the hyperspectral mixed pixel at different component proportion was analyzed. The conclusions are as follows: the correlation between these morphological indexes was obvious, and the best morphological index was chosen by removing the index whose R2 was greater than 0.

[Transperitoneal laparoscopic ureterolithotomy for upper ureteral calculi: a report of 1171 cases].

Objective: To evaluate clinical outcomes and values of transperitoneal laparoscopic ureterolithotomy.

Methods: A total of 1171 patients with upper ureteral calculi were recruited during September 1999 to February 2012. The etiologies included impacted calculi (n = 1100), non-impacted calculi (n = 71), multiple ureteral calculi (n = 51) and combined small calculi in unilateral kidney (n = 139).

[Study on the nonlinear characteristics of the mixed pixel's reflectance in hyperspectral space].

Under the experimental condition of the 50 degree incidence zenith angle and 45 degree detection azimuth, 24 groups of reflectance spectral of the mixed pixel of lotus and water body acquired using the reflex platform and FieldSpec 3 Hi-Res portable spectrum instrument. The hyperspectral space was built based on the reflectance character. The relationship between similarity and the index of lotus area ratio was analyzed using the linear, logarithm and quadratic curve fitting, and the goodness of fitting is 63.

[The relationship between the variation rate of MODIS land surface temperature and AMSR-E soil moisture and its application to downscaling].

Using AMSR-E soil moisture, MODIS land surface temperature (Ts) and vegetation index product, the authors discuss the relationship between the variation rate of land surface temperature and surface soil moisture. Selecting the plains region of central United States as the study area, the authors propose the distribution triangle of the variation rate of land surface temperature and soil moisture. In the present paper, temperature variation and vegetation index (TVVI), a new index containing the information of temperature variation and vegetation, is introduced.

[Investigation of current demands for professional continuing medical education in ophthalmic nurses].

Objective: To investigate the current demands for professional continuing medical education (CME) in ophthalmic nurses and their influential factors, and to provide evidence for properly setting the curriculum of professional CME for nurses.

Methods: Qualitative and quantitative analysis was performed on 60 nurses in an ophthalmic hospital by questionnaire survey and group interview.

Results: Of the nurses surveyed, 49 (81.