Publications by authors named "Gong-Chang Zhang"

Article Synopsis
  • Human brucellosis is a significant public health issue in China, becoming increasingly associated with atypical symptoms like fever of unknown origin (FUO), leading to higher rates of misdiagnosis.* -
  • A study of 35 brucellosis patients revealed that a majority were male, had exposure to livestock, and many were hospitalized due to FUO, which was common in patients with a known epidemiological history.* -
  • The findings suggest that the diagnosis of brucellosis often gets overlooked, especially in FUO cases, highlighting the need for thorough investigations into patients' exposure history and improved diagnostic methods.*
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CO and other chemicals affect mosquito blood meal seeking behavior. Heat, humidity and black color can also serve as orientation cues. However mosquito attraction does not necessarily mean that it will land.

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Nitric oxide (NO) is extensively involved in various growth processes and stress responses in plants; however, the regulatory mechanism of NO-modulated cellular sugar metabolism is still largely unknown. Here, we report that NO significantly inhibited monosaccharide catabolism by modulating sugar metabolic enzymes through S-nitrosylation (mainly by oxidizing dihydrolipoamide, a cofactor of pyruvate dehydrogenase). These S-nitrosylation modifications led to a decrease in cellular glycolysis enzymes and ATP synthase activities as well as declines in the content of acetyl coenzyme A, ATP, ADP-glucose and UDP-glucose, which eventually caused polysaccharide-biosynthesis inhibition and monosaccharide accumulation.

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This review provides new insights that tetrapyrrole signals play important roles in nuclear gene expression, chloroplast development and plant's resistance to environmental stresses. Higher plants contain many tetrapyrroles, including chlorophyll (Chl), heme, siroheme, phytochromobilin and some of their precursors, all of which have important biological functions. Genetic and physiological studies indicated that tetrapyrrole (mainly Mg-protoporphyrin IX) retrograde signals control photosynthesis-associated nuclear gene (PhANG) expression.

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