Publications by authors named "Gong Yongzhan"
Article Synopsis
- - Varicocele is a common condition affecting 10% to 15% of adult males, often causing scrotal pain and testicular issues, with treatments ranging from medication to surgery.
- - Surgical treatment is the most effective option with an 80% success rate, but it comes with risks like bleeding, infection, and recurrence.
- - Recently, transcutaneous neuromuscular electrical stimulation has emerged as a non-invasive alternative for alleviating varicocele-induced pain, showing positive results and highlighting the need for more research to confirm its effectiveness and safety.
Background And Objective: Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme involved in folate metabolism and one-carbon metabolism. MTHFR gene polymorphism affects enzyme activity. MTHFR gene polymorphism is closely related to many human diseases, such as cardiocerebrovascular diseases, diabetes, neural tube defects (NTDs), tumors, and so on.
View Article and Find Full Text PDFObjective: To investigate the clinical efficacy of dapoxetine combined with transcutaneous neuromuscular electrical stimulation (TNES) in the treatment of primary premature ejaculation.
Methods: A total of 60 patients who met the diagnostic criteria for primary premature ejaculation were selected as study subjects and randomly divided into a dapoxetine group (control group) and a dapoxetine combined with percutaneous neuromuscular electrical stimulation group (observation group).30 patients in each group were treated for 4 weeks.
An increasing body of research has demonstrated that appropriate stimulation of the meridians and acupoints in the human body can play a preventative and therapeutic role in diseases. This study combines the use of infrared thermography with intelligent electrophysiological diagnostic system (iEDS) to accurately diagnose and apply transdermal low-frequency electrical stimulation to treat abnormal meridians in patients with erectile dysfunction (ED). The treatment protocol included 6 treatments (each lasting 30 min and performed twice a week).
View Article and Find Full Text PDFProteasome 26S subunit ATPase 4 (PSMC4) could regulate cancer progression. However, the function of PSMC4 in prostate carcinoma (PCa) progression requires further clarification. In the study, PSMC4 and chromobox 3 (CBX3) levels were verified by TCGA data and tissue microarrays.
View Article and Find Full Text PDFErectile dysfunction (ED) is a common disease in males. In the past, the first-line treatment of ED was mainly noninvasive-psychotherapy and oral phosphodiesterase 5 (PDE5) inhibitors. Oral PDE5 inhibitors often need to be used before sexual intercourse and do not repair the pathological damage; hence, the therapeutic effect for secondary ED caused by neurological or endocrine disorders is poor.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to evaluate the effectiveness of transcutaneous neuromuscular electrical stimulation (TNES) in treating erectile dysfunction (ED) in 25 patients over eight months.
- After treatment, significant improvements were observed in various measures of erectile function, such as penile hardness and time of erection, as well as reduced anxiety symptoms, though there were no changes in depression scores.
- TNES proved to be a safe and non-invasive option for improving erectile function and related symptoms in ED patients, suggesting its potential as a new treatment method.