In response to biotic and abiotic stresses, the WRKY gene family plays a crucial role in plant growth and development. This study focused on and involved genome-wide identification of WRKY gene family members, clarification of their molecular evolutionary characteristics, and comprehensive mapping of their expression profiles under diverse abiotic stress conditions. A total of 60 WRKY gene family members were identified, and their phylogenetic classification revealed three distinct groups.
View Article and Find Full Text PDFColorectal cancer is one of the top contributors to cancer-related deaths in the United States, with over 100,000 estimated cases in 2020 and over 50,000 deaths. The most common screening technique is minimally invasive colonoscopy using either reflected white light endoscopy or narrow-band imaging. However, current imaging modalities have only moderate sensitivity and specificity for lesion detection.
View Article and Find Full Text PDFThe effects of austenitizing and austempering temperatures on the bainite transformation kinetics and the microstructural and mechanical properties of a medium-carbon high-silicon ultra-fine bainitic steel were investigated via dilatometric measurements, microstructural characterization and mechanical tests. It is demonstrated that the optimum austenitizing temperature exists for 0.3 wt.
View Article and Find Full Text PDFAdvanced high-strength steels (AHSS) have a wide range of applications in equipment safety and lightweight design, and enhancing the strength of AHSS to the ultra-high level of 2 GPa is currently a key focus. In this study, a new process of thermo-mechanical control process followed by direct quenching and partitioning (TMCP-DQP) was developed based on Fe-0.4C-1Mn-0.
View Article and Find Full Text PDFMorchella esculenta is an edible fungus with a uniquely delicious flavor and remarkable benefits for health. Herein, the molecular mechanism underlying the anti-inflammatory effects of Morchella esculenta was elucidated using molecular docking and network pharmacology. NPASS, Super-pred, SEA, Swiss Target Prediction, GeneCards, DisGeNET, Omim database, and STRING platform were used to select anti-inflammatory targets and construct target protein interaction networks using the active ingredients of Morchella esculenta.
View Article and Find Full Text PDFDisordered solid-solution high-entropy alloys have attracted wide research attention as robust electrocatalysts. In comparison, ordered high-entropy intermetallics have been hardly explored and the effects of the degree of chemical ordering on catalytic activity remain unknown. In this study, a series of multicomponent intermetallic Pt FeCoCuNi nanoparticles with tunable ordering degrees is fabricated.
View Article and Find Full Text PDFBackground: Human acellular dermal matrix (hADM) has found applications in a variety of settings, particularly in breast surgery. The most common hADM is a sheet. Recently, an injectable hADM has been introduced; we compared the biocompatibility and long-term structural integrity of, an injectable hADM and a sheet-type hADM in mice.
View Article and Find Full Text PDFSecond messenger signals, e.g., Ca and cyclic nucleotides, orchestrate a wide range of cellular events.
View Article and Find Full Text PDFSystemic lupus erythematosus (SLE) is a chronic multi-organ autoimmune disease characterized by clinical heterogeneity, unpredictable progression, and flare ups. Due to the heterogeneous nature of lupus, it has been challenging to identify sensitive and specific biomarkers for its diagnosis and monitoring. Despite the fact that the mechanism of SLE remains unknown, impressive progress has been made over the last decade towards understanding how different immune cells contribute to its pathogenesis.
View Article and Find Full Text PDFInt J Environ Res Public Health
January 2023
A series of ecological restoration projects have been proposed to solve ecological problems resulting from human activities. The project of returning farmlands to forests, initiated in 1999, was the most widely implemented ecological restoration project in China. Large amounts of cropland with steep slopes have been converted to forests or grasslands to promote vegetation restoration, reduce soil erosion, and control nonpoint source pollution.
View Article and Find Full Text PDFBackground: Cordycepin is a nucleoside adenosine analog and an active ingredient isolated from the liquid fermentation of . This study sought to explore the mechanism underlying the therapeutic effect of Cordycepin against Alzheimer's disease using network pharmacology and molecular docking technology.
Methods: TCMSP, SYMMAP, CTD, Super-pred, SEA, GeneCards, DisGeNET database, and STRING platform were used to screen and construct the target and protein interaction network of Cordycepin for Alzheimer's disease.
Six α-amylase/subtilisin inhibitor genes () were identified from mulberry (). In this study, bioinformatics and expression pattern analysis of six were performed to determine their roles in resistance to . The expression of all six was significantly increased under infection.
View Article and Find Full Text PDFPublic Health Pract (Oxf)
December 2022
Objectives: Coronavirus disease (COVID-19) outbreaks occurred on ships during the global pandemic of COVID-19. Investigation of the management and outcomes of these outbreaks will help guide future prevention and control strategies for respiratory infectious diseases on ships.
Study Design: Non-systematic narrative review.
Developing low-cost and efficient oxygen evolution electrocatalysts is key to decarbonization. A facile, surfactant-free, and gram-level biomass-assisted fast heating and cooling synthesis method is reported for synthesizing a series of carbon-encapsulated dense and uniform FeNi nanoalloys with a single-phase face-centered-cubic solid-solution crystalline structure and an average particle size of sub-5 nm. This method also enables precise control of both size and composition.
View Article and Find Full Text PDFJ Environ Public Health
September 2022
The evolution of the tourism ecosystem is characterized by its complexity, imbalance, and spatial heterogeneity. As a result, it has been the focus of academic attention across a wide range of disciplines, including geography, ecology, economics, management, sociology, and philosophy. Firstly, this article explores the connotations and characteristics of the spatial evolution of tourism ecosystems, subsequently proposing that the spatial evolution of tourism ecosystems is essentially different and "mutually inclusive.
View Article and Find Full Text PDFChitinase is a hydrolase that uses chitin as a substrate. It plays an important role in plant resistance to fungal pathogens by degrading chitin. Here, we conducted bioinformatics analysis and transcriptome data analysis of the mulberry () chitinase gene family to determine its role in the resistance to .
View Article and Find Full Text PDFZhongguo Zhen Jiu
November 2021
Objective: To review the therapeutic effect of acupuncture and moxibustion on allergic rhinitis based on the network Meta-analysis.
Methods: The randomized controlled trials of acupuncture and moxibustion for allergic rhinitis were retrieved from the databases, starting from the date of establishment to August 17, 2020, i.e.
Background: The Canadian 24-Hour Movement Guidelines for Adults was released in 2020. There is a dearth of evidence on the association between adherence to the 24 h movement guidelines and health indicators. This study aims to (a) explore the associations between potential correlates and meeting the 24 h movement guidelines using a sample of Chinese university students; and (b) examine if meeting 24 h movement guidelines is associated with the severity of anxiety symptoms.
View Article and Find Full Text PDFEvid Based Complement Alternat Med
October 2021
Chronic kidney disease (CKD) is a progressive damage of renal structure and function caused by various reasons. Its course is long and irreversible. CKD can be divided into 5 stages according to the glomerular filtration rate (GFR).
View Article and Find Full Text PDFTo shed light on whether and how firms changed compensation practices in response to a shift in the environment in which they operated, we examine whether there is contagion effect of executive compensation regulation on state-owned enterprises (SOEs) in the emerging market of China. Specifically, we investigate whether firms not directly affected by the changing regulatory environment nonetheless changed executive compensation in response to the actions of the directly affected firms, which is called contagion effect. We further examine the specific contagion mechanisms and the economic consequences of regulation on compensation.
View Article and Find Full Text PDFSmartphone addiction (SPA) affects an increasing number of college students, but it remains poorly understood. This study aimed to explore the psychological mechanism of the decrease in cognitive control ability from cognitive psychology in students with SPA.The smartphone addition tendency scale (MPATS) was used to identify 64 undergraduates with SPA (MPATS > 45) and 64 sex- and age-matched controls (MPATS < 30).
View Article and Find Full Text PDFThis study investigated the prevalence and correlates of mental health outcomes, particularly depression, anxiety, and insomnia, in adolescents with frequent peer victimization experiences (FPVEs). In this cross-sectional study, 490 adolescents reported having FPVEs (prevalence, 4.2%; mean age, 13.
View Article and Find Full Text PDFCobalt-chromium-molybdenum alloys exhibit good mechanical properties (yield strength: ~530 MPa, ultimate tensile strength: ~1114 MPa, elongation-to-failure: ~47.3%, and modulus: ~227 GPa) and corrosion resistance. In recent years, from the perspective of osseointegration, they are considered to be lower in rank in comparison to the widely used titanium alloys.
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