Influence of lung nodule margin on volume- and diameter-based reader variability in CT lung cancer screening.

Objective:: To evaluate the influence of nodule margin on inter- and intrareader variability in manual diameter measurements and semi-automatic volume measurements of solid nodules detected in low-dose CT lung cancer screening.

Methods:: 25 nodules of each morphological category (smooth, lobulated, spiculated and irregular) were randomly selected from 93 participants of the Dutch-Belgian Randomized Lung Cancer Screening Trial (NELSON). Semi-automatic volume measurements were performed using Syngo LungCARE® software (Version Somaris/5 VB10A-W, Siemens, Forchheim, Germany).

Informatics in radiology: postprocessing pitfalls in using CT for automatic and semiautomatic determination of global left ventricular function.

Recent advances in technical capabilities of computed tomographic (CT) scanners, including an increasing number of detector rows, improved spatial and temporal resolution, and the development of retrospective gating, have allowed the acquisition of four-dimensional (4D) datasets of the beating heart. As a result, the heart can be visualized in different phases and CT datasets can be used to assess cardiac function. Many software packages currently exist that allow automatic or semiautomatic evaluation of left ventricular function on the basis of 4D CT datasets.

Accuracy of noninvasive coronary stenosis quantification of different commercially available dedicated software packages.

Purpose: The purpose of this study was to investigate the noninvasive quantification of coronary artery stenosis using cardiac software packages and vessel phantoms with known stenosis severity.

Materials And Methods: Four different sizes of vessel phantoms were filled with contrast agent and scanned on a 64-slice multidetector computed tomography. Diameter and area stenosis were evaluated by 2 observers blinded from the true measures using 5 different software packages.

Evaluation of global left ventricular function assessment by dual-source computed tomography compared with MRI.

Left ventricular (LV) function assessment by dual-source computed tomography (DSCT) was compared with the reference standard method using magnetic resonance imaging (MRI). Accurate assessment of LV function is essential for the prediction of prognosis in cardiac disease. Thirty-four patients undergoing DSCT examination of the heart for various clinical indications underwent MRI after DSCT.