Artificial Intelligence in Epigenetic Studies: Shedding Light on Rare Diseases.

More than 7,000 rare diseases (RDs) exist worldwide, affecting approximately 350 million people, out of which only 5% have treatment. The development of novel genome sequencing techniques has accelerated the discovery and diagnosis in RDs. However, most patients remain undiagnosed.

CAPE: combinatorial absolute phase estimation.

An absolute phase estimation algorithm for interferometric applications is introduced. The approach is Bayesian. Besides coping with the 2pi-periodic sinusoidal nonlinearity in the observations, the proposed methodology assumes a first-order Markov random field prior and a maximum a posteriori probability (MAP) viewpoint.

Phase unwrapping via graph cuts.

Phase unwrapping is the inference of absolute phase from modulo-2pi phase. This paper introduces a new energy minimization framework for phase unwrapping. The considered objective functions are first-order Markov random fields.