[Epidemiologic study of 500 adult epileptics from a hospital population].

An epidemiology analysis is carried out in a hospital population of 500 epileptic patients older than 14 years of age, pertaining to the outpatient department of the Instituto de Neurología, Hospital de Clínicas, Monevideo". This information gathered, corresponds to the period, 1966-1975. Specially formulated records of precoded-type data were used for this research and the data was processed by automation.

[Ischemic cerebral vascular pathology. History and updating].

This is a contribution to the memory of Professor Román Arana Iñíguez. He, with Professor Néstor Azambuja made possible our participation, in the Joint Study of Extracranial Arterial Occlusion from the National Institutes of Health, with 23 U.S.

[Epidemiology of 500 adult epileptics from a hospital population].

On the basis of 500 epileptic patients treated in the Out-Patient Department of the "Instituto de Neurología", Hospital de Clínicas, Montevideo, Uruguay, an epidemiological study is undertaken. Data obtained correspond to the period extending between 1965 and 1975. A precodified data registering system was used and the analysis was done by mechanical processes.

[5 years of experience in the treatment of parkinsonism with L-dopa and its combination with Ro4-4602].

Eighty-one Parkinsonic patients were treated with L-dopa alone and/or combined with Ro4-4602, during 27 to 60 months. The results are reported. 7.

[Long-term syndrome in the treatment of parkinsonism with L-dopa and decarboxylase an inhibitor].

In 28% of patients treated for a long time with L-dopa, alone or combined with a decarboxilase inhibitor, the following "long-term syndrome" was observed: decrease in effectiveness, psychic disorders, intense abnormal movements, distonic attitudes, speech and gait disorders, orthostatic hypotension and/or general reprecussion. In 11% of the patients the "on-off" effect was studied (brisk alteranting Parkinsonic and improved states). Clinical observation during 14 hours a day was repeated with different dosages and different regimes of the drug; these modified the daily variations but did not eliminate the syndrome.

[Long-term syndrome in the treatment of parkinsonism with L-dopa].

A group of 71 patients with Parkinson's disease were treated with L-Dopa and benserazide during periods ranging from 27 to 60 months. In 28% of cases a decline in therapeutic effects and or delayed appearance or increase of secondary actions were observed constituting a long-term syndrome. Its most complex and dramatic expression, the on-off effect, was present in 11% of cases.