Matrix metalloproteinase-9 (GELB) as a member of gelatinases plays key role in the destruction of blood-brain barrier (BBB), T cells migration into the CNS, and demyelination induction. Considering remyelination induction in response to tart cherry extract and pure p-coumaric acid ingestion via tracking MMP9 gene expression in the cuprizone mouse model. Firstly, predicting the chemical interaction between p-coumaric acid and MMP9 protein was conducted through PASS and Swiss dock web services.
View Article and Find Full Text PDFLeishmania spp. are vector-borne flagellates transferred by sand flies. They cause cutaneous, mucocutaneous and visceral infections in mammals, especially in humans and dogs.
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