[The cytogenetic action of antilymphocyte globulin on the lymphocytes of bronchial asthma patients].

Chromosomal aberration levels and frequencies of sister chromatid exchanges (SCE) in peripheral blood lymphocytes were investigated for patients with bronchial asthma treated with antilymphocyte globulin (ALG). The significant elevation of chromosomal aberration levels and SCE frequencies were revealed as compared to the healthy controls. The significant differences in chromosomal aberration levels were not observed before and after the courses of ALG therapy.

[Frequency of sister chromatid exchanges in human lymphocytes at different times of day].

Analysis of the frequency of sister chromatid exchanges in the human blood taken from normal female donors was made at 9 a. m. and 9 p.

[Distribution of the frequency of sister chromatid exchange among Leningrad inhabitants].

Peculiarities of frequency variations in sister chromatid exchanges (SCE) were studied in a group of healthy Leningrad citizens who are not engaged in health-risk industries. No relations were found between the SCE frequency and sex, age and smoking habit (10 cigarettes per day as much). The statistical processing of the data obtained was made taking into account the errors in individual measurements of the SCE frequency.

[Sex ratio in myelocele and anencephaly].

The secondary sex ratio in 254 probands with anencephaly and spina bifida, their 138 sibs and 2492 relatives (sibs of mothers and fathers, sibs of grandmothers and grandfathers) was studied. In anencephaly, girls prevail (males - 29%, p less than 0.001), and in sibs of anencephalic male probands there is a predominance of males (males - 71%, p less than 0.

[Intrauterine selection and human ABO incompatibility. II. Analysis of blood group distribution among 3652 families].

Significant deviations in distribution of compatible and incompatible offspring comparing with expected were discovered in incompatible matings 0XA, 0XB, AXB, BXA. These deviations were not significant in control group of matings AX0, BX0, AXA, BXB. The following phenomenon was observed in rhesus-positive mother with normal pregnancies in incompatible matings: primigravidae in the age group of 25 years and younger had the excess of incompatible children by 24.

[Sex ratio and survival rate in embryogenesis and the perinatal period].

Sex ratio was studied among abortuses and infants who died perinatally (9972 cases). Sex begins influencing mortality in the perinatal period, in which a significant increase in the sex ratio is shown (106 males: 100 females--antenatal; 136 males: 100 females--intranatal; 159 males:100 females--within the first 6 days of life).

[Human sex ratio and sex-related selection at birth].

Sex ratio in 11,500 infants died at different perinatal periods (antenatal, intranatal and postnatal) is studied. Sex ratio in these periods is: 107 male : 100 female; 136 male : 100 female; 168 male : 100 female respectively; differences at each period are statistically significant (alpha less than 0.001).

[Karyotypes of spontaneous human abortuses and several aspects of their phenotypic presentation].

In all, 172 human spontaneous abortuses were examined: 75 cases from the 1st trimester of pregnancy (all were karyotyped), and 97 ones--from 2nd and 3rd trimesters (59 cases were karyotyped). 31 cases of chromosomal anomalies were revealed. The incidence of chromosomal anomalies among the 1st and 2--3rd trimesters of spontaneous abortuses was 40.