[The combined chemotherapy with platinum of patients with inoperable non-small cell lung cancer].

Combination chemotherapy with cyclophosphamide, 5-fluorouracil, adriamycin and platinum was performed in 122 patients with stage III-IV squamous-cell cancer and adenocarcinoma of the lung. Control group included 84 cases of non-small-cell lung cancer treated with the same drugs except platinum. Ten patients with stage III disease received platinum-based combination chemotherapy and split-course radiotherapy in the total dose of 65-70 Gy.

[Effect of correcting liver function on the development of DMBA-induced mammary gland tumors and the metabolism of sex steroid hormones in rats].

The tumours of mammary glands in Wistar rat females were induced by threefold intravenous administration of 7,12-dimethylbenz (a) anthracene (DMBA). The application of pharmacological preparations contributing to the liver function correction (PCLF) in the process of carcinogenesis and during the surgical treatment of mammary tumours leads to prolongation of the first tumour latent period after DMBA administration and of recurrent tumours after the operation. The lowering of the frequency, multiplicity and the rate of mammary tumours growth were also observed.