Publications by authors named "Golnaz Varnaseri"
Context: Oxidative stress and mitochondrial dysfunction are thought to be the main mechanism of T-2 toxin toxicity. T-2 toxin is the most potent trichothecene mycotoxin which is present in agricultural products. L-carnitine, besides its anti-oxidative properties, facilitates the transportation of long-chain fatty acids in to mitochondrial matrix.
View Article and Find Full Text PDFBackground: Traditional medicines are among the oldest medicines and their extensive use in the recent years reflects the public's interest in alternatives to conventional medicine.
Objectives: The aim of this study was to investigate the genotoxicity of Dillsun herbal medicine in DNA damage of rat hepatocytes compared to sodium dichromate using a comet assay technique.
Materials And Methods: Male Wistar rats were caught and their liver was washed with a perfusion buffer, followed by another wash with collagenase buffer.
Background: The increasing use of herbal drugs and their ease of accessibility and availability have necessitated the use of mutagenicity test to analyze their toxicity and safety.
Objectives: This study aimed to evaluate the genotoxicity of Sankol herbal medicine in DNA breakage of rat hepatocytes in comparison with H2O2 by single cell gel electrophoresis technique or comet assay.
Materials And Methods: In the current study hepatocytes were prepared from male wistar rats.
Purpose: The increasing use of herbal drugs and their easy availability have necessitated the use of mutagenicity test to analyze their toxicity and safety. The aim of this study was to evaluate the genotoxicity of Supermint herbal medicine in DNA breakage of rat hepatocytes in comparison with sodium dichromate by single cell gel electrophoresis technique or comet assay.
Methods: Hepatocytes were prepared from male wistar rats and were counted and kept in a bioreactor for 30 minutes.