Toward improving the specificity of perturbation-based training through assessment of dynamic balancing responses: a series of N-of-1 studies in subacute stroke.

Perturbation-based balance training (PBT) has been shown to improve reactive balancing abilities in chronic stroke. To inform future investigations in the subacute phase of stroke, the objective of this series of N-of-1 studies was to investigate the range of balancing responses to unexpected mechanical perturbations applied to the pelvis during walking on an instrumented treadmill before and after PBT training. Three subacute stroke subjects were assessed on each occasion with clinical tests and biomechanical measurements following perturbations applied in forward, backward, inward and outward directions.

A comparison of three balance-assessment scales for patients after stroke with various levels of balance disorder.

It is often difficult for the clinician to choose the most appropriate balance-assessment measure. We wanted to facilitate this decision based on the stroke patient's functional abilities. The aim of our study was to compare three established scales [Berg Balance Scale (BBS), mini-BESTest (MBT) and Functional Gait Assessment (FGA)] in terms of responsiveness, floor and ceiling effects at different levels of ambulation as defined by the Functional Ambulation Classification (FAC).

Assessment of dynamic balancing responses following perturbations during slow walking in relation to clinical outcome measures for high-functioning post-stroke subjects.

Background: Generating appropriate balancing reactions in response to unexpected loss of balance during walking is important to prevent falls. The purpose of this study was to assess dynamic balancing responses following pushes to the pelvis in groups of post-stroke and healthy subjects.

Methods: Forty-one post-stroke subjects and forty-three healthy subjects participated in the study.

Clinical risk factors for post-stroke urinary incontinence during rehabilitation.

Urinary incontinence (UI) is a common problem after stroke. Risk factors for UI seem to be multifactorial. There is still controversy in which risk factors contribute to UI.

Pilot Long-term Evaluation of Competitive and Cooperative Exercise Games in Inpatient Stroke Rehabilitation.

Interpersonal rehabilitation games, which allow patients to compete or cooperate with other patients or unimpaired loved ones, have demonstrated promising short-term results, but have not yet been tested in longer-term studies. This paper thus presents a preliminary 9-session evaluation of interpersonal rehabilitation games for post-stroke arm exercise. Two pairs of stroke survivors were provided with a system that included one competitive and one cooperative rehabilitation game, and exercised with it for 9 sessions in addition to their conventional therapy.

Algorithm for selection of balance assessment tools in post-stroke patients.

The aim of the study was to design an algorithm of selecting the balance assessment tool in patients after stroke, which could be used in a subacute rehabilitation setting. A retrospective study was carried out to analyse results of standardized balance measurements in three groups of stroke patients classified by Functional Ambulation Category (FAC) (FAC 1 or 2, non-functional ambulation; FAC 3 or 4, ambulatory dependent; FAC 5 or 6, ambulatory independent). Balance functions were evaluated in 62 out of 70 patients (88.

Using Inertial Measurement Units and Electromyography to Quantify Movement during Action Research Arm Test Execution.

In patients after stroke, ability of the upper limb is commonly assessed with standardised clinical tests that provide a complete upper limb assessment. This paper presents quantification of upper limb movement during the execution of Action research arm test (ARAT) using a wearable system of inertial measurement units (IMU) for kinematic quantification and electromyography (EMG) sensors for muscle activity analysis. The test was executed with each arm by a group of healthy subjects and a group of patients after stroke allocated into subgroups based on their clinical scores.

A multisession evaluation of an adaptive competitive arm rehabilitation game.

Background: People with neurological injuries such as stroke should exercise frequently and intensely to regain their motor abilities, but are generally hindered by lack of motivation. One way to increase motivation in rehabilitation is through competitive exercises, but such exercises have only been tested in single brief sessions and usually did not adapt difficulty to the patient's abilities.

Methods: We designed a competitive arm rehabilitation game for two players that dynamically adapts its difficulty to both players' abilities.

A novel robot-assisted training approach for improving gait symmetry after stroke.

Gait asymmetry as a consequence of hemiparesis is known as a serious long-term disability, where typical compensatory gait movements are used by stroke subjects in order to cope with their daily activities. This study presents a gait symmetry training approach consisting of the adaptive robot assistance with the combination of the visual feedback integrated in Balance Assessment Robot for treadmill walking (BAR-TM). The support algorithm is based on gait temporal parameters that change the level of assistive support, which was triggered at different gait subphase events.

Rasch validation and comparison of Slovenian, Croatian, and Italian versions of the Mini-BESTest in patients with subacute stroke.

We aimed to verify by Rasch analysis whether the Mini-BESTest, a balance measure, confirms its main psychometric properties in patients with subacute stroke undergoing rehabilitation in three different countries (Slovenia, Croatia, and Italy), and to examine the stability of item hierarchy and difficulty across the three national versions through a differential item functioning analysis. We investigated 159 patients with subacute stroke consecutively admitted to three rehabilitation facilities after screening for an intensive, tailored rehabilitation program. Balance function was tested within 36 h from admission and after ∼25 days.

Overground gait training using a motorized assistive device in patients with severe disabilities after stroke.

Regaining of the patient's ability to walk after stroke is an important goal of rehabilitation programmes. The ultimate goal of gait rehabilitation is to empower patients for overground walking. We have previously developed a prototype of a therapist-controlled mobile platform with compliant pelvis support mechanism that enables balance training during overground walking (device E-go).

Evaluation of a smartphone human activity recognition application with able-bodied and stroke participants.

Background: Mobile health monitoring using wearable sensors is a growing area of interest. As the world's population ages and locomotor capabilities decrease, the ability to report on a person's mobility activities outside a hospital setting becomes a valuable tool for clinical decision-making and evaluating healthcare interventions. Smartphones are omnipresent in society and offer convenient and suitable sensors for mobility monitoring applications.

Effectiveness of a fall-risk reduction programme for inpatient rehabilitation after stroke.

Purpose: To evaluate effectiveness of fall-risk-assessment-based fall prevention for stroke rehabilitation inpatients.

Method: A consecutive series of 232 patients admitted for the first time to a subacute stroke-rehabilitation ward during 2010-2011 was studied in detail. The Assessment Sheet for Fall Prediction in Stroke Inpatients (ASFPSI by Nakagawa et al.

Training of selective attention in work-active stroke patients.

The aim was to examine the effects of computer-based cognitive rehabilitation of attention in work-active patients after stroke. The study included 11 patients treated as inpatients at the University Rehabilitation Institute, Republic of Slovenia, who were included in intensive selective attention training four times a week for 3 months. Each patient was assessed at the initial and the final rehabilitation stage with the TAP system (Test of Attentional Performance), alertness, and divided attention tasks.

Psychophysiological responses to robot training in different recovery phases after stroke.

Psychophysiological responses have become a valuable tool in human-robot interaction since they provide an objective estimate of the user's psychological state. Unfortunately, their usefulness in rehabilitation robotics is uncertain since they are influenced by both physical activity and pathological conditions such as stroke. We performed psychophysiological measurements in subacute and chronic stroke patients as well as healthy controls during a reaching and grasping exercise task performed in a multimodal virtual environment.

Telerehabilitation using virtual reality task can improve balance in patients with stroke.

Purpose: The objective of the telerehabilitation is a continuation of the rehabilitation process on patients' home. The study also compares the balance training in clinical environment with the telerehabilitation approach when the physiotherapists and physicians can follow the progress remotely.

Method: In this paper, the preliminary study of the pilot project with virtual reality (VR)-based tasks for dynamic standing frame supported balance training is presented.

Variable structure pantograph mechanism with spring suspension system for comprehensive upper-limb haptic movement training.

Numerous haptic devices have been developed for upper-limb neurorehabilitation, but their widespread use has been largely impeded because of complexity and cost. Here, we describe a variable structure pantograph mechanism combined with a spring suspension system that produces a versatile rehabilitation robot, called Universal Haptic Pantograph, for movement training of the shoulder, elbow, and wrist. The variable structure is a 5-degree-of-freedom (DOF) mechanism composed of 7 joints, 11 joint axes, and 3 configurable joint locks that reduce the number of system DOFs to between 0 and 3.

Measuring patterns of disability using the International Classification of Functioning, Disability and Health in the post-acute stroke rehabilitation setting.

Objective: To determine whether the International Classification of Functioning, Disability and Health (ICF) model is adequate for assessing disability patterns in stroke survivors in the sub-acute rehabilitation setting in terms of potential changes in functional profiles over time.

Methods: Functional profiles of 197 stroke patients were assessed using the ICF Checklist and the Functional Independence Measure (FIMTM) at admission and discharge from rehabilitation hospital. The ICF Checklist was applied based on medical documentation and rehabilitation team meetings.

Design and test of a novel closed-loop system that exploits the nociceptive withdrawal reflex for swing-phase support of the hemiparetic gait.

A novel closed-loop system for improving gait in hemiparetic patients by supporting the production of the swing phase using electrical stimulations evoking the nociceptive withdrawal reflex was designed. The system exploits the modular organization of the nociceptive withdrawal reflex and its stimulation site- and gait-phase modulation in order to evoke movements of the hip, knee, and ankle joints during the swing phase. A modified model-reference adaptive controller (MRAC) was designed to select the best stimulation parameters from a set of 12 combinations of four electrode locations on the sole of the foot and three different stimulation onset times between heel-off and toe-off.

Functioning and disability in stroke.

Purpose: To describe functioning and disability in patients with stroke according to the model endorsed by the International Classification of Functioning Disability and Health (ICF) in a rehabilitation hospital.

Methods: Adult patients with stroke were consecutively enrolled. The Functional Independence Measure (FIM) and the WHO Disability Assessment Schedule II (WHO-DAS II) were administered in individual sessions.

Improving balance in subacute stroke patients: a randomized controlled study.

The aim of the study was to compare the efficacy of balance training in a balance trainer, a newly developed mechanical device for training balance, with conventional balance training in subacute stroke patients. This was a randomized controlled study. Fifty participants met the inclusion criteria and 39 finished the study.

Normative based clinical tool for objective evaluation of postural responses.

The paper presents a novel normative based method and apparatus for objective assessment of postural responses during unexpected perturbation in clinical environment. A modified standing frame (based on BalanceTrainer) for standing-balance training in a fall-safe balancing environment equipped with electrical actuators to provide unexpected perturbations in eight directions during quiet standing was used. Ground reaction forces were recorded under both feet and center of pressure was calculated to derive postural response indicators.

Dynamic balance training with sensory electrical stimulation in chronic stroke patients.

A case study investigating the impact of sensory electrical stimulation during perturbed stance in one chronic stroke patient is presented. A special apparatus called the BalanceTrainer was used. It allows the application of perturbations to neurologically impaired people during standing, while protecting the subject from falling.

Application of haptic interface for finger exercise.

A haptic device with two active degrees-of-freedom and a tendon-driven transmission system was designed, later on constructed, and submitted to testing. It was embodied as a lightweight mechanism with a small workspace that wraps the finger workspace and can generate forces up to 10 N suitable for finger exercise. The control loop and the user application were implemented on a personal computer in the Microsoft Windows environment.

Grip force tracking system for assessment and rehabilitation of hand function.

The aim of the paper is to present a novel tracking system for the assessment and training of grip force control. The system consists of two force measuring units of different shapes, which can be connected to a personal computer for visual feedback and data acquisition. We present the results of the assessment of the grip force control in 32 healthy subjects of different age groups and preliminary results obtained in a patient after head-injury who was treated with Botulinum-Toxin for hand spasticity.