[Hemodynamic disorders in the acute period of myocardial infarct according to the radiocardiographic data].

Changes in central hemodynamics in patients suffering from acute macrofocal and transmural myocardial infarction with or without circulatory insufficiency were studied by radiocardiography. Cardiac output was found to be increased in the first 24 hours of the disease in persons without circulatory insufficiency as compared to the control group, which may be linked with marked activation of the sympatheticoadrenal system. In the groups of patients with circulatory insufficiency the cardiac output during this period was diminished.

[Use of Hyperstat for arresting hypertensive crises].

The indices of central hemodynamics were determined in 112 patients with hypertensive disease during a crisis and in its arrest with hyperstat by means of integral rheography. The condition of the sympatheticoadrenal and kallikrein-kinin systems was studied. It was found that hyperstat normalizes arterial pressure in 5--6 minutes by reducing the initially increased general peripheral resistance and increasing the blood stroke and minute volumes as well as by reducing the content of adrenaline.

[Intensive therapy and resuscitation of heart rhythm disorders in myocardial infarct patients and the role of express methods of controlling respiratory function].

The authors used a complex of express methods to examine respiration and acid-base equilibrium in the unit of intensive care and therapy. Examination by means of these methods during intensive therapy and resuscitation helps in individualizing the therapeutic measures. Various individual disorders of respiration were revealed during electroimpulse therapy in paroxysms of tachyarrhythmia, but the final effect of this treatment in restoration of the sinus rhythm had a beneficial influence on the dynamics of cardiogenic respiratory insufficiency.

[Combined use of glucagon and strophanthin in myocardial infarct complicated by severe cardiac insufficiency].

The effects of isolated and combined use of strophanthin and glucagon on the values of central hemodynamics and cardiac contractile function were compared. The study was conducted on patients with myocardial infarction complicated by congestive heart failure in the acute period of the disease. It was found that a combination of these drugs had a synergic inotropic effect.

[Experience in using integral rheography for evaluating the hemodynamic indices in emergency states in cardiology].

The work deals with the comparative assessment of integral rheography, a modern method for studying hemodynamic indices. As compared to the method of dye dilution and radiocardiography, integral rheography has proved to be sufficiently precise and at the same time has definite advantages as a method of express diagnosis in patients with acute cardiovascular diseases. As compared with the other method of indirect determination of the cardiac output, tetrapolar rheography, integral rheography is more suitable for being used in emergencies, particularly in cases with disorders of the rhythm of the cardiac activity.

[Certain characteristics of central hemodynamics in acute period of myocardial infarct].

Changes in the indices of central hemodynamics and contractility of the heart muscle in the acute period of macrofocal myocardial infarction were studied. In many cases heart ejection and performance of the left ventricle in the first 24 hours of the disease were greater than those in the control group of patients with ischemic heart disease in the period of remission. The increase coincided in time with sharp activation of the sympathico-adrenal and other systems of the organism in myocardial infarction, occurred on a background of deteriorated cardiac contractility, and ended by the third day of the acute period.

[Therapy and prevention of different forms of ventricullar fibrillation in myocardial infarct].

Data on 80 cases of myocardial infarction complicated by different forms of ventricular fibrillation (VF)--primary, secondary and recurrent--are analysed. VF was shown to be accompanied by distinct disorders in respiration, metabolism and haemodynamics. Metabolic disorders are characterized by acid-base and electrolyte balance changes, increased activity of the adrenal glands, and increased release of catecholamines and glucocorticoids into the blood.

Changes in sympatho-adrenal and kallikrein-kinin systems in the terminal stage of extensive myocardial infarction.

Fifty patients with acute extensive myocardial infarction, with unfavourable course, were continuously survelled from the beginning of the disease till the terminal stage with the aim to study the interdependences between changes in the sympatho-adrenal and kallikrein-kinin systems in blood. The blood levels of adrenaline and noradrenaline were determined fluorometrically. The activity of the kallikrein-kinin system was estimated on the basis of three components: spontaneous esterase activity, prekallikrein activity, and kallikrein inhibitor activity in blood.

[External heart rupture in myocardial infarct (clinical picture, prospects for resuscitation)].

An analysis is presented on 53 cases of external ruptures of the heart in cases of transmural myocardial infarction. Most of the patients were above 60 years of age, with a hypertensive syndrome, with intensive, protracted, often recurring cardiac and retrosternal pains. The pains were interpreted as the manifestation of myocardial rupture.