Publications by authors named "Golik A"

Currently, biopolymer-based Zn-containing nanoforms are of great interest for medical applications. However, there is lack information on optimal synthesis parameters, reagents and stabilizing agent for production of zinc carbonate nanoparticles (ZnC-NPs). In this work, synthesis of ZnC-NPs was carried out by chemical precipitation with the use of chitosan, hydroxyethyl cellulose, methyl cellulose and hyaluronic acid as stabilizing agents.

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This work demonstrates the first time synthesis of selenium nanoparticles (Se NPs) stabilized with neonol. The synthesis method was optimized using a multifactorial experiment with three input parameters. The most stable sample had a radius of 15 nm and a ζ-potential of -36.

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Detergents and disinfectants for dairy industry must meet a variety of characteristics, including low toxicity, high antibacterial activity, and excellent rinsing of pollutants from working surfaces. This work presents an innovative detergent-disinfectant agent based on whey mineralizate and silver nanoparticles (Ag NPs), which allows reducing production costs and ensuring high cleanliness of treated surfaces compared to analogues. For this purpose, a method for obtaining sols of Ag NPs stabilized with didecyldimethylammonium bromide (Ag NPs-DDAB) was developed and optimized using neural network algorithms.

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Article Synopsis
  • Synthesis and characterization of a chitosan-ricobendazole complex demonstrated optimal ratios and successful molecular formation, confirmed by advanced techniques.
  • Scanning electron microscopy showed the complex's spherical particles, with sizes between 100 to 200 μm, indicating successful physical properties.
  • Therapeutic trials on sheep showed the chitosan-ricobendazole complex had a high efficiency of 89%, comparable to 92% for a commercial drug, and effectively reduced helminth egg counts, highlighting its potential in treatment.
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This study discovered and examined novel triple chelate complexes involving iron, ascorbic acid, and essential amino acids (AsA-Fe-AmA triple chelate complexes) for the first time. The mechanism of complex formation was studied using FTIR spectroscopy and quantum chemical modeling. The produced complexes were shown to be suitable for fortifying food items with a pH of 3-7 that have not been exposed to heat treatment at temperatures over 75 °C for more than 15 min.

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This study aimed to synthesize, characterize, and evaluate the effect of cocamidopropyl betaine-stabilized MnO nanoparticles (NPs) on the germination and development of pea seedlings. The synthesized NPs manifested as aggregates ranging from 50-600 nm, comprising spherical particles sized between 19 to 50 nm. These particles exhibited partial crystallization, indicated by peaks at 2θ = 25.

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Selenium nanoparticles (Se NPs) have a number of unique properties that determine the use of the resulting nanomaterials in various fields. The focus of this paper is the stabilization of Se NPs with cetyltrimethylammonium chloride (CTAC). Se NPs were obtained by chemical reduction in an aqueous medium.

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Purpose: The curriculum of the Adelson School of Medicine at Ariel University, the newly established sixth medical school in Israel, includes a simulation center-based extended course on physician-patient communication, aiming to help students master the core competency of interpersonal and communication skills. For more than a year following the emergence of the COVID-19 pandemic, the school suspended most face-to-face (F2F) encounters, transforming most teaching activities to remote platforms. The paper outlines the ways we adapted teaching of this course to these circumstances, the reactions of students and mentors to the changes and results of 1st year students' survey.

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Article Synopsis
  • Entomotherapy is the medicinal use of insects, with a long history and over 2100 edible species, but its potential as an alternative to traditional medicine is still underexplored.
  • The review identifies 235 insect species used for healing, particularly focusing on the Hymenoptera, and their properties, such as anti-inflammatory and antimicrobial effects, mainly targeting digestive and skin issues.
  • Challenges like regulatory issues, consumer acceptance, and overexploitation of insect populations must be addressed for entomotherapy to evolve into a sustainable and affordable treatment option in the future.
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The aim of this research was to study the effect of MnO nanoparticles stabilized with L-methionine on the morphofunctional characteristics of the barley ( L.) crop. MnO nanoparticles stabilized with L-methionine were synthesized using potassium permanganate and L-methionine.

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The purpose of this work was to study the effect of selenium nanoparticles (Se NPs) on the biological and morphofunctional parameters of barley seeds (Hordéum vulgáre L.) We used seeds of Hordéum vulgáre L. with reduced morphofunctional characteristics.

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In this work, CeO nanoparticles, as well as CeO nanocomposites with plasmonic silver nanoparticles, were synthesized using a simple sol-gel process. The concentration of silver in the composites varied from 0.031-0.

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Article Synopsis
  • - This article discusses the synthesis of selenium nanoparticles (Se NPs) stabilized by a quaternary ammonium compound through a chemical reduction process in water, optimizing the synthesis method via multifactorial experiments.
  • - The size and stability of the Se NPs were analyzed using techniques like dynamic light scattering, where negatively charged particles showed a bimodal size distribution (45 nm and 1-10 nm) while positively charged particles had a diameter of about 70 nm.
  • - The study also examined how pH levels and ionic strength affected the stability of Se NPs, finding that stable aggregates existed between pH 2 and 6 but degraded in alkaline conditions, with ionic interactions also influencing nanoparticle size based on charge.
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A method for the synthesis of ZnO nanoparticles (ZnO NPs) gels was developed. ZnO NPs were obtained through a sol-gel method with zinc acetate usage as a precursor. Optimization of the method of synthesis of ZnO NPs gel has been carried out.

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Importance: Early behavior problems in children with developmental delay (DD) are prevalent and impairing, but service barriers persist. Controlled studies examining telehealth approaches are limited, particularly for children with DD.

Objective: To evaluate the efficacy of a telehealth parenting intervention for behavior problems in young children with DD.

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In this work, selenium nanoparticles (Se NPs) stabilized with cocamidopropyl betaine were synthesized for the first time. It was observed that Se NPs synthesized in excess of selenic acid had a negative charge with ζ-potential of -21.86 mV, and in excess of cocamidopropyl betaine-a positive charge with ξ =  + 22.

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In the present study, a method for the synthesis of gelatin-stabilized copper oxide nanoparticles was developed. Synthesis was carried out by direct chemical precipitation. Copper sulfate, chloride, and acetate were used as precursors for the copper oxide synthesis.

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Objectives: Infectious diseases in pregnant women can cause birth defects. Implementing appropriate prevention methods while planning pregnancy can help avoid some of them.

Material And Methods: A cross-sectional survey study was performed.

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In this work, we obtained silver nanoparticles stabilized with polyvinylpyrrolidone, ranging in size from 70 to 110 nm, which exhibits good crystallinity and anisotropic structure. For the first time, we studied the influence of the molar ratio of silver between silver and peroxide on the oxidation process of the nanoparticles and determined the regularities of this process by analyzing changes in absorption spectra. Our results showed that at molar ratios of Ag:HO = 1:1 and 1:5, dependences of changes in the intensity, position and half-width of the absorption band of the plasmon resonance are rectilinear.

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Benzene, toluene, ethylbenzene, and xylene (BTEX) are a group of volatile organic compounds that are ubiquitous in the environment due to numerous anthropogenic sources. Exposure to BTEX poses a health hazard by increasing the risk for damage to multiple organs, neurocognitive impairment and birth defects. Urinary BTEX metabolites are useful biomarkers for the evaluation of BTEX exposure, because of the ease of sampling and their longer physiological half-lives compared with parent compounds.

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Background: Patients hospitalized with acute heart disease [acute myocardial infarction (MI); heart disease exacerbation] may require red blood cell (RBC) transfusion. These patients are at increased risk for morbidity and mortality. Hematological biomarkers may help to identify increased mortality risk.

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Background: Hypomagnesemia (serum magnesium level < 1.7 mg/dl) occurs more frequently in patients with type 2 diabetes mellitus (T2DM).Serum magnesium levels are not routinely tested in hospitalized patients, including in hospitalized patients with T2DM.

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