Evaluation of a Web-based decision aid for people considering the APOE genetic test for Alzheimer risk.

Purpose: With the increasing interest in apolipoprotein E (APOE) genetic testing to estimate the risk of developing late-onset Alzheimer disease, new educational tools are needed to help people make the best decision for themselves about whether to undergo this test. This study evaluated an online tool to assist in this decision process.

Methods: A prototype decision aid was studied in a two-part survey that collected data from participants before and after they examined the decision aid.

African americans may have to consume more than 12 grams a day of resistant starch to lower their risk for type 2 diabetes.

African Americans have a high prevalence rate of type 2 diabetes mellitus (DM). High-maize 260 (National Starch and Chemical Co., Bridgewater, NJ, USA) resistant starch (RS) is a promising food ingredient to reduce risk factors for type 2 DM.

Isoflavones improve plasma homocysteine status and antioxidant defense system in healthy young men at rest but do not ameliorate oxidative stress induced by 80% VO2pk exercise.

Aims: (1) Determination of whether isoflavones, as antioxidants and estrogen-like substances, reduce the atherosclerotic process. (2) Assessment of isoflavone anti-atherosclerotic effectiveness by means of measuring plasma markers of atherosclerosis: homocysteine (Hcy), antioxidant status, and lipid peroxidation. (3) Testing of isoflavone antioxidant effectiveness in the presence and absence of oxidative stress induced by exercise.